CD30-positive primary cutaneous lymphoproliferative disorders: molecular alterations and targeted therapies [PDF]
Primary cutaneous CD30-positive T-cell lymphoproliferative disorders are the second most common subgroup of cutaneous T-cell lymphomas. They include two clinically different entities with some overlapping features and borderline cases: lymphomatoid ...
Lucia Prieto-Torres+5 more
doaj +7 more sources
Cutaneous T-Cell Lymphoma in Asians [PDF]
Cutaneous T-cell lymphoma describes a heterogeneous group of neoplasms of skin homing T cells that vary considerably in clinical presentation, histologic appearance, immunophenotype, and prognosis. This paper addresses the cutaneous T-cell lymphoma in Asians with respect to clinical-epidemiologic and histopathological features.
Min Soo Jang+4 more
openaire +6 more sources
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma [PDF]
T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones+7 more
doaj +2 more sources
Silent T-cell receptor cutaneous T-cell lymphoma associated to a clonal plasma cell proliferation [PDF]
Within T-cell lymphomas (TCL) there are 2 entities expressing gamma-delta TCR: hepatosplenic gamma-delta T-cell lymphoma (HSGDTL) and the primary cutaneous gamma-delta T-cell lymphoma (PCGDTL).
Ana Caballero+6 more
doaj +3 more sources
Update on primary cutaneous T-cell lymphomas rare subtypes [PDF]
Rare subtypes of cutaneous T-cell lymphomas (CTCL) include four entities, primary cutaneous γδ T-cell lymphoma, primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma, and primary cutaneous CD4+ small/medium T-cell ...
Silvia Alberti-Violetti, Emilio Berti
doaj +3 more sources
Round Cells of the Epidermis: Clues from Studies on Neoplastic Lymphocytes of Cutaneous T Cell Lymphoma [PDF]
Neoplastic cells of cutaneous T cell lymphoma (CTCL) appear to be of monoclonal origin and frequently are nonspecific helpers of normal B cell differentiation.
Richard L. Edelson
openalex +2 more sources
Functional Characterization of Neurotensin Receptors in Human Cutaneous T Cell Lymphoma Malignant Lymphocytes [PDF]
Cutaneous T cell lymphomas are a clonal proliferation of CD4+ T lymphocytes primarily involving the skin. Mycosis fungoides is an epidermotropic CD4+ cutaneous T cell lymphoma, and a more aggressive form, Sezary syndrome, occurs when the malignant cells ...
Mohamed Ramez+8 more
openalex +3 more sources
Mycosis fungoides, also known as cutaneous T-Cell lymphoma, is a rare hematologic malignancy characterized by cutaneous involvement. There is significant variability in dermatologic presentation in early stages and often atypical pathology findings on ...
Larsen, Tyler, Ojeaburu, Leslie
core +1 more source
Primary cutaneous T-cell lymphoma: experience from the Peruvian National Cancer Institute [PDF]
: Background: Primary cutaneous T-cell lymphomas constitute a heterogeneous and rare group of diseases with regional particularities in Latin America.
Rosana Ruiz+5 more
doaj +1 more source
Mycosis fungoides and Sézary syndrome belong to the group of primary cutaneous T-cell lymphomas. Because of the inflammatory appearance of the skin lesions, we hypothesized that antimicrobial peptides might be dysregulated in these conditions, similar to
Ulrike Wehkamp+3 more
doaj +1 more source