Results 41 to 50 of about 241,686 (283)
Metal shearing energy absorber [PDF]
, 1973 A metal shearing energy absorber is described. The absorber is composed of a flat thin strip of metal which is pulled through a slot in a cutter member of a metal, harder than the metal of the strip.
Fay, R. J., Wittrock, E. P.
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Preliminary Test of Prescribed Burning for Control of Maple Leaf Cutter (Lepidoptera: Incurvariidae) [PDF]
, 2017 Leaf litter burning in the spring resulted in 87.5% mortality of maple leaf cutter pupae, Paraclemensia acerifoliella (Fitch).
Ball, J. +3 more
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Meitan kexue jishu, 2023 The cutterhead was one of the key parts of the Tunneling Boring Machine to achieve tunnel mining. Cutterhead’s continuous breaking rock was the rock destruction process under the cutter group.
Yadi LIU +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Investigating the performance of TiN and TiAIN coatings on milling cutter used for machining bimetal steel strip [PDF]
, 2009 Surface engineering of cutting tools (single point or multipoint) through advanced coatings (e.g., TiN) has contributed towards considerable improvement of tool life, productivity and machining quality [1] by modifying the tool substrate.
Haider, Julfikar, Sarwar, Mohammed
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
DETAILS’ REPAIR OF CONSTRUCTION AND ROAD MACHINES: FLUCTUATIONS’ MODELLING
Вестник СибАДИ, 2019 Introduction. Hole details are quite widely used in structures of construction and road machines. The specialists apply boring for draft, semi-fair, and in some cases for fair processing of such surfaces.
V. E. Ovsyannikov, V. I. Vasilyev
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Applied Sciences, 2020 Cutter edge temperature in milling is an important factor to cutter life. With high cutting speed and feedrate, the cutting efficiency is high; however, the cutter edge temperature is high, shortening the cutter life.
Qi Deng +3 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source