Results 31 to 40 of about 89,685 (265)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Journal of Advanced Mechanical Design, Systems, and ManufacturingWhile machining spiral bevel gear by forming method, the stability of cutting force acts a significant element affecting tool wear and machining performance.
Zhen WANG +4 more
doaj +1 more source
Research on PCBN Tool Dry Cutting GCr15
Machines, 2018 This paper is based on the theoretical analysis designs of a dry cutting orthogonal test in order to study a phenomenon that the radial force is larger than the main cutting force when a PCBN (polycrystalline cubic boron nitride) tool hard turns GCr15 ...
Qinghua Li +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A Model for Predicting Dynamic Cutting Forces in Sand Mould Milling with Orthogonal Cutting
Chinese Journal of Mechanical Engineering, 2018 Cutting force is one of the research hotspots in direct sand mould milling because the cutting force directly affects the machining quality and tool wear. Unlike metals, sand mould is a heterogeneous discrete deposition material. There is still a lack of
Zhong-De Shan, Fu-Xian Zhu
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
An investigation on the cutting force of milling Inconel 718
MATEC Web of Conferences, 2018 Inconel alloy has been widely used in industry but is difficult to machine due to its rapid change in cutting force during machining. This paper investigated the cutting force for milling Inconel 718 as conventional force model is unable to handle the ...
Tsai Jhy-Cherng +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Geomechanics and Geophysics for Geo-Energy and Geo-ResourcesUnderstanding the distribution of cutting force provides a foundation for the design and optimization of cutterhead layout. The simulation of rotary cutting with a large cutting radius remains a challenge for laboratory tests.
Long-Chuan Deng +6 more
doaj +1 more source