Results 81 to 90 of about 3,826,227 (356)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Cutting Force and Cutting Quality during Tapered Milling of Glass Magnesium Board
Applied Sciences, 2019 In this paper, the effects of tool geometry and cutting parameters on cutting force and quality were investigated during the tapered milling of glass magnesium (MGO) board with diamond cutters. The results were as follows: firstly, both the cutting force
Pingxiang Cao +5 more
doaj +1 more source
DEM simulation of soil-tool interaction under extraterrestrial environmental effects [PDF]
, 2017 In contrast to terrestrial environment, the harsh lunar environment conditions include lower gravity acceleration, ultra-high vacuum and high (low) temperature in the daytime (night-time).
Arroyo Alvarez de Toledo, Marcos +3 more
core +2 more sources
Force-frequency effect of Y-cut langanite and Y-cut langatate [PDF]
IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 2003 Most recently, langasite and its isomorphs (LGX) have been advanced as potential substitutes for quartz, owing to their extremely high-quality (Q) factors. At least twice higher Q value of LGX than that of quartz has been reported. High Q translates into potentially greater stability.
Yoonkee, Kim, Arthur, Ballato
openaire +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Metal: Jurnal Sistem Mekanik dan Termal, 2020 Milling machine is a machine that cuts a workpiece using a plural chisel that rotates on a freis machine. During the freis process, the material is cut because of the cutting force that occurs between the tool and the workpiece.
Firman Ridwan, Refki Harvendri
doaj +1 more source
Prediction of Cutting Forces by using Machine Parameters in end Milling Process [PDF]
Engineering and Technology Journal, 2008 Cutting forces produce deformations along cutting tool which is one ofthe mechanical machining errors, so that cutting force during a millingoperation can be simulated in tool geometry during cutting conditionand workpiece, then studying this forces to ...
Abbas Fadhel Ibraheem +2 more
doaj +1 more source
Design of an instrumented smart cutting tool and its implementation and application perspectives [PDF]
, 2014 This paper presents an innovative design of a smart cutting tool, using two surface acoustic wave (SAW) strain sensors mounted onto the top and the side surface of the tool shank respectively, and its implementation and application perspectives.
Chen, X +4 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Investigation of Cutting Force in Longitudinal-Torsional Ultrasonic-Assisted Milling of Ti-6Al-4V
Materials, 2019 In this study, we propose a longitudinal-torsion ultrasonic-assisted milling (LTUM) machining method for difficult-to-cut materials—such as titanium alloy—in order to realize anti-fatigue manufacturing.
Ying Niu, F. Jiao, Bo Zhao, G. Gao
semanticscholar +1 more source