Results 81 to 90 of about 3,023,757 (394)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Design and Study on the Cutting Structure of Rotary Cutting PDC Bit
Shiyou jixie, 2020 The rotary cutting PDC bit can well adapt to deep high-plasticity strata. In this paper, the cutting performance of rotary cutting PDC bit was investigated by means of experiment and simulation.
Cao Yang, Wang Haitao
doaj
Research into mechanical modeling based on characteristics of the fracture mechanics of ice cutting for scientific drilling in polar regions [PDF]
The CryosphereScientific drilling in polar regions plays a crucial role in obtaining ice cores and using them to understand climate change and to study the dynamics of polar ice sheets and their impact on global environmental changes (sea level, ocean current cycle ...
X. Lv +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Cutting Force Prediction in Drilling of Titanium Alloy
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2012 Cutting force in drilling of Ti-6Al-4V is studied with simulation based on a predictive model. In the force model, three-dimensional chip flow is made by piling up the orthogonal cuttings in the planes containing the cutting velocities and the chip flow ...
Shoichi TAMURA +2 more
doaj +1 more source
From large-scale to micro machining: a review of force prediction models [PDF]
, 2013 In this paper, a reviewof work performed in the area of force modelling in metal cutting processes is presented. Past and present trends are described and criticised to compare their relevance with current requirements.
FROMENTIN, Guillaume +4 more
core
Tactile perception by tissue force characteristics for robotic red eat cutting [PDF]
This research investigates an approach to tactile perception for guiding a cutting tool attached to a robotic system processing red meat. Conventional tactile sensing methods, reliant solely on spatial force values, have met with inconsistent results ...
Aly, Basem Adel Ahmed
core +1 more source
, 2023 The surface roughness of a part during external cylindrical grinding is directly impacted by cutting force and vibration, which are intermediate parameters. To improve the quality of finished parts, studying and controlling these parameters is essential.
Nguyen, Linh Tuan +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
An investigation on the mechanics of nanometric cutting and the development of its test-bed
, 2003 The mechanics of machining at a very small depth of cut (100 nm or less) is not well understood. The chip formation physics, cutting forces generation, resulting temperatures and the size effects significantly affect the efficiency of the process and ...
Cheng, K, Guo, XJ, Luo, X, Holt, R
core +1 more source