Results 91 to 100 of about 2,344,781 (356)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Журнал інженерних наукToday, micro-milling of NiTi alloys is used to manufacture precision mechanisms, instrumentation, space technology, micro-electro-mechanical systems, biomedical devices, and implants. It is becoming increasingly widespread.
Nataliia Balytska +2 more
doaj +1 more source
FEA modeling of orthogonal cutting of steel: a review [PDF]
, 2012 Orthogonal cutting is probably the most studied machining operation for metals. Its simulation with the Finite Element Analysis (FEA) method is of paramount academic interest.
Borzan, Marian +3 more
core +1 more source
Diamond turning of soft semiconductors to obtain nanometric mirror surfaces [PDF]
, 2002 Diamond cutting is a viable alternative to grinding and polishing in the fabrication of high-quality soft semiconductors. Investigation of indentation provides useful information for understanding the practical diamond cutting process of brittle ...
Fang, Fengzhou Z. +2 more
core +1 more source
Applied Composite Materials, 2017 Machining Glass fibre aluminium reinforced epoxy (GLARE) is cumbersome due to distinctively different mechanical and thermal properties of its constituents, which makes it challenging to achieve damage-free holes with the acceptable surface quality.
K. Giasin +3 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Indirect monitoring method of tool wear using the analysis of cutting force during dry machining of Ti alloys [PDF]
, 2017 In recent decades, optimize tool life is in constant evolution so many researchers have focused to analysis the tool wear by indirect monitoring (e.g. acoustic emission, cutting forces, vibrations) that plays a significant role in control and improvement
Marcos, Mariano +3 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Machinability analysis on helical milling of carbon fiber reinforced polymer
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2015 In the helical milling process, a rotating tool traverses a helical trajectory to generate a hole. In order to investigate the cutting state in helical milling of carbon fiber reinforced polymer(CFRP), experiments were conducted with unidirectional and ...
Haiyan WANG, Xuda QIN, Hao LI
doaj +1 more source
PLoS ONE, 2022 To investigate the cutting forces on road-header picks, a series of full-scale single-pick rotary cutting tests on sandstone samples were conducted at the National Engineering Laboratory of Coal Mining Machinery and Equipment, China.
Qianqian Zhang +4 more
doaj +1 more source