Results 101 to 110 of about 66,719 (305)

Cutting Forces Prediction in the Dry Slotting of Aluminium Stacks [PDF]

, 2014
Cutting forces are one of the inherent phenomena and a very significant indicator of the metal cutting process. The work presented in this paper is an investigation of the prediction of these parameters in slotting processes of UNS A92024-T3 (Al-Cu ...
SALGUERO, Jorge, MARCOS, Mariano, CALAMAZ, Madalina, GIROT, Franck, BATISTA, Moises   +4 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A new material model for 2D numerical simulation of serrated chip formation when machining titanium alloy Ti-6Al-4V [PDF]

, 2008
A new material constitutive law is implemented in a 2D finite element model to analyse the chip formation and shear localisation when machining titanium alloys. The numerical simulations use a commercial finite element software (FORGE 2005) able to solve
CALAMAZ, Madalina, GIROT, Franck, COUPARD, Dominique   +2 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Study of the System of Forces Acting on the Cutter-Oscillator Under Conditions of Turning With Vibration

Shock and Vibration
This paper investigates the forces acting on a cutter-oscillator during free longitudinal orthogonal turning under regenerative self-oscillation conditions.
Pavlo Tryshyn, Serhiy Dyadya, Olena Kozlova   +2 more
doaj   +1 more source

Effects of machining parameters, ultrasonic vibrations and cooling conditions on cutting forces and tool wear in meso scale ultrasonic vibrations assisted end-milling (UVAEM) of Ti–6Al–4V under dry, flooded, MQL and cryogenic environments – A statistical analysis

Journal of Materials Research and Technology
Ti–6Al–4V, an alloy of titanium has recently gained focus of research to overcome its machinability challenges. Miniaturization in devices has forced a shift towards micro and meso-scale machining.
Adil Rauf, Muhammad Ali Khan, Syed Husain Imran Jaffery, Shahid Ikramullah Butt   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Online Tool Wear Monitoring by the Analysis of Cutting Forces in Transient State for Dry Machining of Ti6Al4V Alloy

Metals, 2019
In this work, the analysis of the cutting speed and feed rate influence on tool wear and cutting forces in Ti6Al4V alloy dry machining is presented. The study has been focused on the machining in a transient state.
Yezika Sánchez Hernández, F. Javier Trujillo Vilches, Carolina Bermudo Gamboa, Lorenzo Sevilla Hurtado   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source