Results 101 to 110 of about 189,838 (273)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Simulation of Drilling Process for Control of Burr Formation
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010 An analytical force model is presented to simulate the cutting force and the chip flow direction in the drilling process. Three dimensional chip flow is interpreted as a piling up of the orthogonal cuttings in the planes containing the cutting velocities
Takashi MATSUMURA, Jürgen LEOPOLD
doaj +1 more source
The generalized minimum spanning tree problem [PDF]
, 2000 We consider the Generalized Minimum Spanning Tree Problem denoted by GMSTP. It is known that GMSTP is NP-hard and even finding a near optimal solution is NP-hard.
Kern, W., Pop, P.C., Still, G.J.
core +2 more sources
Efficient Algorithms for Moral Lineage Tracing
, 2017 Lineage tracing, the joint segmentation and tracking of living cells as they move and divide in a sequence of light microscopy images, is a challenging task. Jug et al.
Andres, Bjoern +6 more
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Journal of Applied Mathematics, 2012 We investigate solving semidefinite programs (SDPs) with an interior point method called SDP-CUT, which utilizes weighted analytic centers and cutting plane constraints. SDP-CUT iteratively refines the feasible region to achieve the optimal solution. The
John Machacek, Shafiu Jibrin
doaj +1 more source
Unfolding Orthogonal Terrains [PDF]
, 2007 It is shown that every orthogonal terrain, i.e., an orthogonal (right-angled) polyhedron based on a rectangle that meets every vertical line in a segment, has a grid unfolding: its surface may be unfolded to a single non-overlapping piece by cutting ...
O'Rourke, Joseph
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
CrystalsIn this study, a visualized microstructure evolution model for the primary shear zone during NiTi smart alloy machining was established by integrating an analytical cutting model with a cellular automaton method.
Jiaqi Wang +9 more
doaj +1 more source
Some lower bounds on sparse outer approximations of polytopes [PDF]
, 2014 Motivated by the need to better understand the properties of sparse cutting-planes used in mixed integer programming solvers, the paper [2] studied the idealized problem of how well a polytope is approximated by the use of sparse valid inequalities.
Dey, Santanu S. +2 more
core