Results 61 to 70 of about 926,491 (359)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Threaded pilot insures cutting tool alignment [PDF]
, 1966 Threaded pilot allows machining of a port component, or boss, after the reciprocating hole has been threaded.
Goldman, R., Schneider, W. E.
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Numerical Study of the Effects of Tool Parameters on the Cutting Temperature Distribution and Ignition Risks of Magnesium Alloys [PDF]
, 2022 Linfeng Li +3 more
openalex +1 more source
Design and analysis of a piezoelectric film embedded smart cutting tool [PDF]
, 2012 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Institution of Mechanical Engineers.The condition of a cutting tool is an important factor for manufacturing processes.
Cheng, K, Rakowski, R
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Health Hazard Manual For Cutting Oils, Coolants, and Metalworking Fluids [PDF]
, 1991 [Excerpt] The metalworker can be exposed to cutting oils during application by two basic routes of entry: skin contact and inhalation. The higher risk jobs tend to be those with high cutting speeds, heavy oil flow, and continuous contact, which may ...
Brown, Nellie J
core +1 more source
An experimental study of the effect of high-pressure water jet assisted turning (HPWJAT) on the surface integrity [PDF]
, 2011 This study deals with the effect of High-Pressure Water Jet Assisted Turning (HPWJAT) of austenitic stainless steels on chip shape and residual stresses. The machining of the austenitic stainless steels represents several difficulties. Recently, research
HABAK, Malek, LEBRUN, Jean-Lou
core +4 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
DESIGNING AND DEVELOPING A PROGRAM IN SINUMERIK vs. 1.3 FOR A SHAFT WITH SEALING GROOVES [PDF]
Fiabilitate şi Durabilitate, 2015 CNC is an abbreviation for „Computer Numerically Controlled". Numerically controlled tool machines are also called CNC machines.The numeric control results in a process of continuous „feeding” of an especially built programable controller, with a set ...
VALERIA VICTORIA IOVANOV
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