Results 71 to 80 of about 892,705 (358)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
DESIGNING AND DEVELOPING A PROGRAM IN SINUMERIK vs. 1.3 FOR A SHAFT WITH SEALING GROOVES [PDF]
Fiabilitate şi Durabilitate, 2015 CNC is an abbreviation for „Computer Numerically Controlled". Numerically controlled tool machines are also called CNC machines.The numeric control results in a process of continuous „feeding” of an especially built programable controller, with a set ...
VALERIA VICTORIA IOVANOV
doaj
Refrigerated cutting tools improve machining of superalloys [PDF]
, 1971 Freon-12 applied to tool cutting edge evaporates quickly, leaves no residue, and permits higher cutting rate than with conventional coolants.
Dudley, G. M.
core +1 more source
The effect of an organic pentasulfide EP additive in turning and milling operations [PDF]
, 2014 Coopération avec Ecole Centrale LyonBecause a cutting fluid could be equally used for different cutting operations, this study proposed to investigate the behavior of a well-known extreme-pressure additive (pentasulfide) in both turning and milling ...
BIERLA, Aleksandra +4 more
core +4 more sources
Laser Prepared Cutting Tools [PDF]
Physics Procedia, 2012 AbstractLaser pulses with a pulsewidth of a few picoseconds have recently received a lot of attention, solving the problem of manufacturing tools for new materials of superior mechanical properties. Processing thermally sensitive material, such as diamond and CBN structures, can be done without major material deterioration effects.
Dold Claus +3 more
openaire +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Machinability improvement using high-pressure cooling in turning
Research in Agricultural Engineering, 2014 Process fluids are used primarily for their cooling and lubricating effect in machining. Many ways to improve their performance have been proposed; the analysis of some of them is provided in the paper.
R. Drlička, V. Kročko, M. Matúš
doaj +1 more source
Threaded pilot insures cutting tool alignment [PDF]
, 1966 Threaded pilot allows machining of a port component, or boss, after the reciprocating hole has been threaded.
Goldman, R., Schneider, W. E.
core +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Chaotic vibrations in a regenerative cutting process
, 2001 We have analyzed vibrations generated in an orthogonal cutting process. Using a simple one degree of freedom model of the regenerative cutting we have observed the complex behaviour of the system.
Chatterjee +11 more
core +1 more source