Results 71 to 80 of about 926,491 (359)
Machinability improvement using high-pressure cooling in turning
Research in Agricultural Engineering, 2014 Process fluids are used primarily for their cooling and lubricating effect in machining. Many ways to improve their performance have been proposed; the analysis of some of them is provided in the paper.
R. Drlička, V. Kročko, M. Matúš
doaj +1 more source
Tool post modification allows easy turret lathe cutting-tool alignment [PDF]
, 1966 Modified tool holder and tool post permit alignment of turret lathe cutting tools on the center of the spindle. The tool is aligned with the spindle by the holder which is kept in position by a hydraulic lock in feature of the tool post. The tool post is
Fouts, L.
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Friction and Wear of Cutting Tools and Cutting Tool Materials
LubricantsThe friction between cutting tools and the workpiece/chip can significantly affect the tool wear, cutting force, cutting temperature, machined surface integrity, and machined parts’ service performance [...]
Guoliang Liu +4 more
openaire +3 more sources
Reliability assessment of cutting tool life based on surrogate approximation methods [PDF]
, 2014 A novel reliability estimation approach to the cutting tools based on advanced approximation methods is proposed. Methods such as the stochastic response surface and surrogate modeling are tested, starting from a few sample points obtained through ...
Kolios, Athanasios +1 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Investigation of tool geometry effect and penetration strategies on cutting forces during thread milling [PDF]
, 2014 The application of thread milling is increasing in industry because of its inherent advantages over other thread cutting techniques. The objective of this study is to investigate the effect of milling cutter tool geometry on cutting forces during thread ...
BRENDLEN, Romain +3 more
core +3 more sources
Design of an instrumented smart cutting tool and its implementation and application perspectives [PDF]
, 2014 This paper presents an innovative design of a smart cutting tool, using two surface acoustic wave (SAW) strain sensors mounted onto the top and the side surface of the tool shank respectively, and its implementation and application perspectives.
Chen, X +4 more
core +1 more source
Investigation on Cutting Performance of Micro-Textured Cutting Tools [PDF]
Micromachines, 2019 This paper explores the influence of micro textures on cutting performance of polycrystalline cubic boron nitride (PCBN) tools from two aspects, that is, tool wear and machined surface roughness. By designing micro-hole textures with different forms and scales on the rake face of tools when PCBN tools turn hardened steel GCr15, and combining finite ...
Li, Pan, Jiao, Hu
openaire +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source