Results 81 to 90 of about 892,705 (358)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Identifying the cause of cutting tool failure by using simulation software
MATEC Web of Conferences, 2018 The article is focused on the construction problems of cutting tools designed for manufacturing components in high numbers. Analysis of the tool with low lifetime is provided with the use of simulation software to detect the causes of the tool failure ...
Zrak Andrej, Koňár Radoslav
doaj +1 more source
Estimation of residual life of a cutting tool used in a machining process [PDF]
MATEC Web of Conferences, 2018 A significant part of cost of machining is associated with non-optimum use of cutting tool. Moreover cutting tool failure is responsible for almost 20% of the machining downtime.
Ghosh Sourath +2 more
doaj +1 more source
Modelling and simulation on the tool wear in nanometric cutting [PDF]
, 2003 Tool wear is a significant factor affecting the machined surface quality. In this paper, a Molecular Dynamics (MD) simulation approach is proposed to model the wear of the diamond tool in nanometric cutting. It includes the effects of the cutting heat on
Cheng, K, Holt, R, Luo, X
core
Cutting-edge industrial technology of mining tool manufacturing [PDF]
, 2016 Purpose. To conduct a comparative economic analysis of cermet alloys regeneration technology, to identify the most “environmentally friendly” and cost-effective processing of solid alloys waste. Methods.
Gurenko, A, Naumenko, O, Savchenko, Iu
core +2 more sources
Evaluation of Cutting Tool Parameters [PDF]
Procedia Engineering, 2014 AbstractEvaluation of the cutting tool is an important aspect when a machining process is monitored. At this time, microgeometry of the cutting edge is very frequently used term. It has a great influence on the cutting process and it is necessary to know how correctly to measure parameters of the cutting edge to ensure reliability and repeatability ...
Ivana Česáková +2 more
openaire +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Tool post modification allows easy turret lathe cutting-tool alignment [PDF]
, 1966 Modified tool holder and tool post permit alignment of turret lathe cutting tools on the center of the spindle. The tool is aligned with the spindle by the holder which is kept in position by a hydraulic lock in feature of the tool post. The tool post is
Fouts, L.
core +1 more source
Dynamic analysis of runout correction in milling [PDF]
, 2010 Tool runout and its effects is an important area of research within modelling, simulation, and control of milling forces. Tool runout causes tool cutting edges to experience uneven forces during milling.
Diez Cifuentes, Eduardo +3 more
core +2 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source