Results 121 to 130 of about 19,999 (211)
ELR positive CXCL chemokines are highly expressed in an animal model of ulcerative colitis
Journal of Inflammation Research, 2019 Mohammad Amin Boshagh,1,2 Poorya Foroutan,1,2 Mohammad Raman Moloudi,3 Shohreh Fakhari,1 Parisa Malakouti,1 Bahram Nikkhoo,1 Ali Jalili1,21Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran; 2Department of ...
Boshagh MA +6 more
doaj
CXC chemokines located in the 4q21 region are up-regulated in breast cancer. [PDF]
, 2007 International audienceRecent data suggest that chemokines could be essential players in breast carcinogenesis. We previously showed that the CXC chemokine CXCL8 (interleukin-8) was overexpressed in estrogen receptor alpha (ERalpha)-negative breast cell ...
Chavey, Carine +9 more
core +1 more source
Memorias do Instituto Oswaldo Cruz, 2006 Chemokines are a superfamily of low-molecular-weight cytokines that were initially described for their chemoattractant activity. It is now clear chemokines have several other activities that modulate immune processes.
Adriano LS Souza +4 more
doaj +1 more source
Inflammatory signatures in the spectrum of myeloid diseases
HemaSphere, Volume 10, Issue 7, July 2026.Abstract Dysregulated innate immunity contributes to clonal cytopenias and myeloid neoplasms, but its extent across disease stages and clinical relevance remain incompletely defined. We analyzed plasma ASC/NLRP3 double‐positive (DP) specks, ASC single‐positive (SP) specks, and 45 cytokines in 223 patients with idiopathic cytopenias of undetermined ...
Alice Ibbotson +12 more
wiley +1 more source
Aging Cell, Volume 25, Issue 7, July 2026.Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang +7 more
wiley +1 more source
Pharmacological ResearchProstate cancer (PC) and Ovarian cancer (OC) are two of the most common types of cancer that affect the reproductive systems of older men and women. These cancers are associated with a poor quality of life among the aged population.
Amin Ullah +4 more
doaj +1 more source
Identification of therapeutic targets and prognostic biomarkers among CXC chemokines in hepatocellular carcinoma microenvironment. [PDF]
Cancer Biomark, 2023 Yin Z, Ma T, Chen S, Yu M.
europepmc +1 more source
Evidence for a Two‐Step Model for Activation of GPR25 by the Chemoattractant CXCL17
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.ABSTRACT CXCL17 was recently reported to activate GPR25, a receptor expressed by T‐regulatory cells. Although classified as a chemokine, the activity of CXCL17 is ablated by minor C‐terminal truncation, suggesting a novel mode of receptor activation. We set out to test this hypothesis by mutagenesis. GPR25 was expressed in the murine pre‐B cell line L1.
Wuqing Yang +2 more
wiley +1 more source
Type I and II Interferon Signalling Characterizes the Transcriptional Landscape of Sweet Syndrome
Experimental Dermatology, Volume 35, Issue 7, July 2026.ABSTRACT Sweet syndrome (SS) is an autoinflammatory neutrophilic dermatosis characterized by abrupt‐onset inflammatory skin lesions and systemic symptoms, yet its molecular pathogenesis remains incompletely defined. To delineate disease‐specific inflammatory programmes, we performed NanoString‐based transcriptomic analysis of SS skin lesions and ...
Laura Calabrese +12 more
wiley +1 more source
Chemokines and Their Role in Parasitic Diseases
European Journal of Inflammation, 2004 Chemotactic cytokines (chemokines), the intercellular mediators, produced and released by a wide variety of cell types, are a group of small secreted proteins (8–10 KDa), which mediate host response to invading organisms (viruses, bacteria, parasites ...
S. Frydas +5 more
doaj +1 more source