Results 121 to 130 of about 68,560 (212)

Temporal relationships between circulating levels of CC and CXC chemokines and developing atherosclerosis in apolipoprotein E*3 Leiden mice

, 2003
CC and CXC chemokines are implicated in leukocyte recruitment during development of atherosclerotic lesions, suggesting circulating levels of chemokines may be useful serum markers of atherogenesis.
Overend, Philip, Vidgeon-Hart, Martin, Graham, Annette, Grimsditch, David .., Benson, G. Martin, Murphy, Nuala, Bruckdorfer, K. Richard, Groot, Pieter H.E.   +7 more
core   +1 more source

Associations of Serum CIRP and CXCL5 With Prognosis and Neutrophil Extracellular Traps in Pediatric Mycoplasma pneumoniae Pneumonia

The Clinical Respiratory Journal, Volume 20, Issue 10, October 2026.
This study investigated serum levels of cold‐inducible RNA‐binding protein (CIRP) and C‐X‐C motif chemokine ligand 5 (CXCL5) in 485 children with Mycoplasma pneumoniae pneumonia. Elevated levels of both biomarkers were independently associated with poor prognosis and positively correlated with neutrophil extracellular trap markers, suggesting their ...
Litao Wan, Bolin Liu, Ning Xie, Jianhua Li, Ting Su, Liyan Zhang, Xiaohua Wang, Shiding Gao   +7 more
wiley   +1 more source

Mast-cell-dependent secretion of CXC chemokines regulates ischemia-reperfusion-induced leukocyte recruitment in the colon.

, 2008
BACKGROUND AND AIMS: Recruitment of leukocytes in the tissue microvasculature is considered to be a rate-limiting step in ischemia-reperfusion (I/R)-induced inflammation. The objective of this study was to examine the role of mast cells in CXC-chemokine-
Yusheng Wang, Wang, Yusheng, Thorlacius, Henrik, Jeppsson, Bengt, Stefan Santen, Menger, Michael, Bengt Jeppsson, Michael D. Menger, Santén, Stefan, Henrik Thorlacius, Wang, Yusheng,, Thorlacius, Henrik,, Lund University., Santén, Stefan,, Jeppsson, Bengt,   +14 more
core   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

European Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman, Sreya Rahman, Francesca Polverino, Muhammad Adrish   +3 more
wiley   +1 more source

Expression of IP-10 Chemokine is Regulated by Pro-inflammatory Cytokines in Cultured Hepatocytes

Iranian Journal of Allergy, Asthma and Immunology, 2007
Chemokines are classified in four distinct groups as CXC, CC, CX3C and C, depending on the presence or absence of a motif called ELR (Arg-Leu-Glu) before the first cysteine residue in their structure. CXC chemokines are also subdivided into ELR+ and ELR-.
Gholamhossein Hassanshahi, Abdollah Jafarzadeh, Zohreh Ghorashi, Nazanin Zia Sheikholeslami, Alan James Dickson   +4 more
doaj  

CXC chemokine receptor type 5 may induce trophoblast dysfunction and participate in the processes of unexplained missed abortion, wherein p-ERK and interleukin-6 may be involved

Heliyon
Chemokines regulate the trophoblast dysfunction involved in the occurrence and development of pathological pregnancy, including missed abortions. In particular, CXC chemokine receptor type 5 mediates cell proliferation, migration, and inflammation ...
Yanan Zhi, Pingping Zhang, Yan Luo, Yanmei Sun, Juan Li, Mingming Zhang, Yali Li   +6 more
doaj   +1 more source

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, Volume 59, Issue 10, Page 2143-2163, October 2026.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Comprehensive analysis of the prognosis and immune infiltration for CXC chemokines in colorectal cancer. [PDF]

Aging (Albany NY), 2021
Yang X, Wei Y, Sheng F, Xu Y, Liu J, Gao L, Yang J, Sun X, Huang J, Guo Q.   +9 more
europepmc   +1 more source

Ras regulates alveolar macrophage formation of CXC chemokines and neutrophil activation in streptococcal M1 protein-induced lung injury.

, 2014
Streptococcal toxic shock syndrome (STSS) is associated with a high mortality rate. The M1 serotype of Streptococcus pyogenes is most frequently associated with STSS. Herein, we examined the role of Ras signaling in M1 protein-induced lung injury.
Thorlacius, Henrik, Rahman, Milladur, Milladur Rahman, Rundk Hwaiz, Songen Zhang, Zhang, Songen, Hwaiz, Rundk, Herwald, Heiko, Heiko Herwald, Henrik Thorlacius, Rahman, Milladur,, Zhang, Songen,, Hwaiz, Rundk,, Thorlacius, Henrik,, Lund University., Herwald, Heiko,   +15 more
core   +1 more source

Circulating granulocyte colony‐stimulating factor as a sex‐unbiased global marker of lung and colorectal cancer cachexia pre‐clinical models

Experimental Physiology, Volume 111, Issue 10, Page 4705-4721, 1 October 2026.
Abstract Cancer cachexia, affecting up to 80% of patients with advanced cancer, is characterized by metabolic and inflammatory dysregulation driven by tumour‐ and host‐derived factors. Although cytokines are central to cachexia pathogenesis, their circulating profiles and transcriptional relevance across models and sexes remain incompletely defined. We
Francielly Morena, Eleanor R. Schrems, Ana Regina Cabrera, Ruqaiza Muhyudin, Sepideh Shakeri, Stavroula Tsitkanou, Mark Viggars, Tyrone A. Washington, Nicholas P. Greene   +8 more
wiley   +1 more source