A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Chemokines regulate the trophoblast dysfunction involved in the occurrence and development of pathological pregnancy, including missed abortions. In particular, CXC chemokine receptor type 5 mediates cell proliferation, migration, and inflammation ...
Yanan Zhi +6 more
doaj +1 more source
Comprehensive analysis of the prognosis and immune infiltration for CXC chemokines in colorectal cancer. [PDF]
Yang X +9 more
europepmc +1 more source
Expression of IP-10 Chemokine is Regulated by Pro-inflammatory Cytokines in Cultured Hepatocytes
Chemokines are classified in four distinct groups as CXC, CC, CX3C and C, depending on the presence or absence of a motif called ELR (Arg-Leu-Glu) before the first cysteine residue in their structure. CXC chemokines are also subdivided into ELR+ and ELR-.
Gholamhossein Hassanshahi +4 more
doaj
Molecular evidence for the existence of two distinct IL-8 lineages of teleost CXC-chemokines [PDF]
Interleukin-8 (IL-8) is a CXC-type chemokine with a chemotactic activity mainly on neutrophils and plays a key role in promoting inflammation. In teleosts, several CXC-chemokines have been cloned and characterized as being IL-8-like.
加藤-鵜木, 陽子 +10 more
core
Correlation analysis of expression of CC and CXC chemokines in children with autism spectrum disorder. [PDF]
Peng G +5 more
europepmc +1 more source
Functions of CXC chemokines as biomarkers and potential therapeutic targets in the hepatocellular carcinoma microenvironment. [PDF]
Wang J +7 more
europepmc +1 more source
Bioinformatics, Molecular Docking and Experiments In Vitro Analyze the Prognostic Value of CXC Chemokines in Breast Cancer. [PDF]
Wang F, Yuan C, Wu HZ, Liu B, Yang YF.
europepmc +1 more source
Bioinformatics Analysis of Potential Therapeutic Targets and Prognostic Biomarkers amid CXC Chemokines in Ovarian Carcinoma Microenvironment. [PDF]
Jin Y +6 more
europepmc +1 more source

