Results 111 to 120 of about 68,560 (212)

The proinflammatory CXC-chemokines GRO-alpha/CXCL1 and MIG/CXCL9 are concomitantly expressed in ulcerative colitis and decrease during treatment with topical corticosteroids

, 2007
Background Ulcerative colitis is characterized by relapsing mucosal inflammation where the lesions include tissue-damaging granulocytes. In addition, T cells and natural killer (NK) cells play important pathophysiologic roles.
Marie Carlson, Bjartell, Anders, Carlson, Marie, Arne Egesten, Sangfelt, Per,, Egesten, Arne, Carlson, Marie,, Mette Eliasson, Erjefält, Jonas S., Anders I. Olin, Olin, Anders, Anders Bjartell, Jonas S. Erjefält, Eliasson, Mette, Erjefält, Jonas, Olin, Anders I., Sangfelt, Per, Per Sangfelt, Erjefält, Jonas,, Olin, Anders,, Egesten, Arne,, Bjartell, Anders,, Lund University., Eliasson, Mette,   +23 more
core   +1 more source

Pulsed Focused Ultrasound–Mediated Mechanopriming Enhances the Therapeutic Efficacy of Mesenchymal Stromal Cell–Derived Extracellular Vesicles in Acute Respiratory Distress Syndrome

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Extracellular vesicles (EVs) derived from mesenchymal stem or stromal cells (MSCs) have shown therapeutic potential for acute respiratory distress syndrome (ARDS), yet reproducible and scalable methods to enhance EV yield and therapeutic potency remain limited.
Shashank Chetty, Shobha Regmi, Abantika Ganguly, Reza Yarani, Fantahun Biadglegne Degeneh, Rosita Primavera, Jing Wang, Avnesh S. Thakor   +7 more
wiley   +1 more source

Pro-inflammatory cytokines and CXC chemokines as game-changer in age-associated prostate cancer and ovarian cancer: Insights from preclinical and clinical studies' outcomes

Pharmacological Research
Prostate cancer (PC) and Ovarian cancer (OC) are two of the most common types of cancer that affect the reproductive systems of older men and women. These cancers are associated with a poor quality of life among the aged population.
Amin Ullah, Yongxiu Chen, Rajeev K. Singla, Dan Cao, Bairong Shen   +4 more
doaj   +1 more source

Knockdown of CLEC7A Alleviates Ischemic Brain Injury by an Anti‐Inflammatory Microglial Phenotype via the CXCL1/CXCR2 Axis

Journal of Neuroscience Research, Volume 104, Issue 10, October 2026.
Integrated bioinformatics analysis of GEO datasets identified CLEC7A as a key hub gene in ischemic stroke. In vitro (OGD model with BV2 microglia/HT22 neuron co‑culture) and in vivo (rat MCAO model) experiments demonstrated that CLEC7A knockdown reduced apoptosis, suppressed inflammation, decreased infarct size, and attenuated brain injury ...
Min Xi, Meipin Yang, Tianyi Xu, Chunhua Yun, Hui Lu, Zhenqiang Zhao, Jiying Li, Jijun Li, Yingting Fu, Yunyu Li, Wei Li   +10 more
wiley   +1 more source

Identification of therapeutic targets and prognostic biomarkers among CXC chemokines in hepatocellular carcinoma microenvironment. [PDF]

Cancer Biomark, 2023
Yin Z, Ma T, Chen S, Yu M.
europepmc   +1 more source

Mycobacterium bovis bacillus Calmette–Guérin (BCG) induces human CC- and CXC-chemokines in vitro and in vivo

, 2006
Summary Both CC- and CXC-chemokines are known to be potent leucocyte activators and chemoattractants and play important roles in inflammatory responses.
Y Luo, X Chen, M A O'Donnell
core   +1 more source

Molecular evidence for the existence of two distinct IL-8 lineages of teleost CXC-chemokines

Interleukin-8 (IL-8) is a CXC-type chemokine with a chemotactic activity mainly on neutrophils and plays a key role in promoting inflammation. In teleosts, several CXC-chemokines have been cloned and characterized as being IL-8-like.
加藤-鵜木, 陽子, ナカオ, ミキ, Abdelkhalek, Nevien K., カトウ－ウノキ, ヨウコ, 杣本, 智軌, Kato-Unoki, Yoko, ソマモト, トモノリ, Komiya, Asuka, 中尾, 実樹, Somamoto, Tomonori, Nakao, Miki   +10 more
core  

Role of Extracellular Vesicles in Shaping Immune Responses in the Lymph Node Microenvironment

Biology of the Cell, Volume 118, Issue 10, October 2026.
Functional alliances of stromal, innate and adaptive immune cells in EV immunity in the lymph node. EV reflect the phenotype of their mother cell and cluster material from their surroundings. In the lymph node, EV preserve valuable context information between multiple cellular effectors to coordinate immunity in adaption to change.
Alicia Charrier, Apolline Salama, Laurence Dubreil, Grégoire Mignot, Steffi Bosch   +4 more
wiley   +1 more source

Integrative Multi‐Omics and Experimental Validation Define RELB as an Immune‐Related Prognostic Driver in Ovarian Cancer

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
Integrated multi‐omics identified key genes associated with the immune microenvironment in ovarian cancer, and functional assays validated the role of key genes in ovarian cancer. ABSTRACT Ovarian cancer (OC) is one of the most aggressive gynecological malignancies worldwide.
Wenshu Leng, Xingyue Fan, Yichen Fang
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, Volume 59, Issue 10, October 2026.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source