Results 91 to 100 of about 68,032 (209)

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Re: Chemokines in Cancer

, 2016
Chemokines are chemotactic cytokines that regulate the trafficking and positioning of cells by activating the seven-transmembrane spanning G protein-coupled chemokine receptors (GPCR) or non G protein-coupled seven-transmembrane spanning receptors called
Fehmi Narter
core   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Additional file 2 of Screening of CXC chemokines in the microenvironment of ovarian cancer and the biological function of CXCL10

, 2021
Additional file 2: Supplementary Figure 1. Oncomine database analysis of the expression of different chemokines. Supplementary Figure 2. The prognostic value of different expressed CXC chemokines in OC patients in the disease free survival curve ...
Weiyuan Li (9619499), Chunjie Xiao (8891636), Xun Sheng (11728257), Ji-Ao Ma (11728254)   +3 more
core   +1 more source

ANGIOGENIC AND ANGIOSTATIC CHEMOKINES LEVEL IN NORMAL SYNOVIAL FLUID

Медицинская иммунология, 2014
Chemokines are believed to play an important role in immunopathogenesis of different joint diseases. One of important problems in studies of synovial fluid is determination of normal level of chemokines from control patients.
D. A. Zhebrun, A. L. Maslyanskiy, A. G. Titov, A. P. Patruhin, A. A. Kostareva, N. A. Arsentieva, N. E. Lubimova, A. V. Semenov, Areg A. Totolian   +8 more
doaj   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes [PDF]

, 2012
Cytokines play an important role in ischemic injury and repair. However, little is known about their prognostic value in cardiovascular disease. The aim of this study was to investigate the prognostic importance of chemokines CCL3/MIP-1α, CCL5/RANTES and
van Dieijen-Visser, Marja P., Brenda W. C. Bongaerts (134222), Erik A. L. Biessen (132311), Michael Weber (134225), Brenda W C Bongaerts, Stefanie Dimmeler (134234), van Berkel, Theo J. C., Patty J. Nelemans (134239), Michael Weber, Mat Rousch (134231), Kitty B. J. M. Cleutjens (134238), Jager, Saskia C. A. de, Dieijen-Visser, Marja P. van, Cleutjens, Kitty B. J. M., Nelemans, Patty J., Biessen, Erik A. L., Mat Rousch, Bongaerts, Brenda W. C., Saskia C A de Jager, Marja P. van Dieijen-Visser (134236), Weber, Michael, Marja P van Dieijen-Visser, Adriaan O. Kraaijeveld (134229), Berkel, Theo J. C. van, Rousch, Mat, Biessen, Erik A. L.; id_orcid, de Jager, Saskia C. A., Theo J C van Berkel, Adriaan O Kraaijeveld, Stefanie Dimmeler, Dimmeler, Stefanie, Kraaijeveld, Adriaan O., Theo J. C. van Berkel (132307), Kitty B J M Cleutjens, Erik A L Biessen, Patty J Nelemans, Saskia C. A. de Jager (134219)   +36 more
core   +1 more source

Evolutionarily conserved mechanisms regulating stress-induced neutrophil redistribution in fish

Frontiers in Immunology
IntroductionStress may pose a serious challenge to immune homeostasis. Stress however also may prepare the immune system for challenges such as wounding or infection, which are likely to happen during a fight or flight stress response.MethodsIn common ...
Katarzyna Klak, Katarzyna Klak, Magdalena Maciuszek, Lukasz Pijanowski, Magdalena Marcinkowska, Magdalena Marcinkowska, Joanna Homa, B. M. Lidy Verburg-van Kemenade, Krzysztof Rakus, Magdalena Chadzinska   +9 more
doaj   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source