Results 221 to 230 of about 62,416 (259)

CXCL10 in psoriasis

Advances in Medical Sciences, 2015
Chemokine (C-X-C motif) ligand (CXCL)10 is involved in the pathogenesis of psoriasis. It has been demonstrated that chemokine (C-X-C motif) receptors (CXCR)3 and CXCL10 were detected in keratinocytes and the dermal infiltrate obtained from active psoriatic plaques and that successful treatment of active plaques decreased the expression of CXCL10 ...
Silvia Martina Ferrari, Ilaria Ruffilli, Michele Colaci   +2 more
exaly   +6 more sources

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CXCL10 and autoimmune diseases

Autoimmunity Reviews, 2009
CXCL10 is a 10 kDa protein, which is categorized functionally as a Th1-chemokine. It binds to the receptor CXCR3 and regulates immune responses through the activation and recruitment of leukocytes, such as, T cells, eosinophils, and monocytes. Recent reports have shown that serum and/or tissue expressions of CXCL10 are increased in various autoimmune ...
Eun Young Lee, Yeong Wook Song
exaly   +3 more sources

CXCL9 and CXCL10 bring the heat to tumors

Science Immunology, 2022
CXCL9 and CXCL10 can be produced by antigen-presenting cells (dendritic cells or macrophages) and by tumor cells. Hoch et al. demonstrated that CXCL9 and CXCL10 co-localize with LAG3 + T cells expressing CCL4 or CXCL13 and contribute to the generation
Robin Reschke, Thomas F. Gajewski
openaire   +2 more sources

CXCR3, CXCL10 and type 1 diabetes

Cytokine and Growth Factor Reviews, 2014
Type 1 diabetes (T1D) is due to antigen-specific assaults on the insulin producing pancreatic β-cells by diabetogenic T-helper (Th)1 cells. (C-X-C motif) ligand (CXCL)10, an interferon-γ inducible Th1 chemokine, and its receptor, (C-X-C motif) receptor (CXCR)3, have an important role in different autoimmune diseases. High circulating CXCL10 levels were
Alessandro Antonelli, Silvia Martina Ferrari, Alda Corrado   +2 more
exaly   +3 more sources

Role of CXCL10 in cryoglobulinemia.

Clinical and experimental rheumatology, 2015
Interferon (IFN)-γ-induced protein 10 (IP-10/CXCL10) and its receptor, C-X-C motif receptor 3, appear to contribute to the pathogenesis of hepatitis C virus (HCV)-related mixed cryoglobulinaemia (MC) (HCV+MC). The secretion of CXCL10 by cluster of differentiation (CD) CD4+, CD8+, and natural killer-T cells is dependent on IFN-γ, which is itself ...
Mazzi V, Ferrari SM, Giuggioli D, ANTONELLI, ALESSANDRO, Ferri C, Fallahi P.   +5 more
openaire   +3 more sources

CXCL10: A candidate biomarker in transplantation

Clinica Chimica Acta, 2012
Interferon (IFN) γ-induced protein 10 kDa (IP-10) or C-X-C motif chemokine 10 (CXCL10) is a small cytokine belonging to the CXC chemokine family. This family of signaling molecules is known to control several biological functions and to also play pivotal roles in disease initiation and progression.
ROMAGNANI, PAOLA, CRESCIOLI, CLARA
openaire   +3 more sources

Synergistic antitumor effect of CXCL10 with hyperthermia

Journal of Cancer Research and Clinical Oncology, 2007
IFN-inducible protein 10 (IP-10)/CXCL10 (CXC chemokine ligand 10) has been described as an antiangiogenic chemokine and displays a potent antitumor activity in vivo. In the present study, we try to investigate whether the combination therapy of hyperthermia, a physical antiangiogenic modality, with CXCL10 would completely eradicate the established ...
Ping, Chen, Ling-Lin, Yang, Han-Shuo, Yang, Yong-Sheng, Wang, Gang, Li, Yang, Wu, Fang, Fang, Kang, Liu, Jie, Li, Xia, Zhao, Huo-Zhen, Hu, Yu-Quan, Wei   +11 more
openaire   +2 more sources

[CXCR3 and CXCL10 in autoimmune thyroiditis].

La Clinica terapeutica, 2014
The chemokine (C-X-C motif) ligand 10 (CXCL10, also called IP-10) was initially identified as a chemokine that is induced by interferon (IFN)-γ. CXCL10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3). CXCL10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific ...
Ruffilli, I, FERRARI, Silvia Martina, COLACI, Michele, FERRI, Clodoveo, Politti, U, Antonelli, A, Fallahi, P.   +6 more
openaire   +3 more sources

The effects of CXCL10 polymorphisms on COPD susceptibility

Molecular Genetics and Genomics, 2017
The polymorphisms of cytokine genes has been reported to modulate the individual's susceptibility to environmental stimuli in COPD development. C-X-C motif chemokine 10 (CXCL10) mediates recruitment inflammatory cells such as monocytes. Therefore, it may play a key role in COPD.
Yan, Wang, Qipeng, Zhou, Lian, Dong, Mingmei, Xiong, Hua, Jiang, Meihua, Guo, Li, Zhao, Liang, Yuan, Ziying, Li, Hanwei, Liu, Jian, Wang, Nanshan, Zhong, Wenju, Lu   +12 more
openaire   +2 more sources

Prognostic and predictive values of CXCL10 in colorectal cancer

Clinical and Translational Oncology, 2020
The role of CXCL10 in progression and prognosis of colorectal cancer (CRC) has been studied for years, yet results remain controversial.This study aims to explore the relationship between CXCL10 and CRC progression and prognosis.We evaluated plasma CXCL10 in CRC patients using ELISA.
J. Chen, Q.-L. Chen, W.-H. Wang, X.-L. Chen, X.-Q. Hu, Z.-Q. Liang, Y.-b. Cao, Y.-M. Cao, S.-B. Su   +8 more
openaire   +2 more sources