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The good side of CXCL10 in cancer
Science Signaling, 2021CXCL10 signaling prevents, rather than promotes, progression of premalignant pancreatic neoplasia.
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The role of CXCL10 in cartilage development and diseases
CytokineCXC motif chemokine ligand 10 (CXCL10), also known as interferon γ-induced protein 10 kDa, is a pleiotropic member of the CXC chemokine family and plays a potent role in cellular functions and pathophysiological processes, which include but are not limited to recruitment of immune cells, induction of cellular apoptosis, regulation of cell growth and ...
Xi, Cao +3 more
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A Role for the CXCR3/CXCL10 Axis in Rasmussen Encephalitis
Pediatric Neurology, 2013Rasmussen encephalitis is a devastating pediatric syndrome of unknown etiology that is characterized by progressive loss of neurological function and intractable focal epilepsy. Cytotoxic T lymphocytes have an active role in the pathogenic process of Rasmussen encephalitis.
Isabel, Mirones +8 more
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Human Immunology, 2017
Genetic variations in chemokine genes influence the chemoattractive properties of T cells which may be associated with outcome of infections. In present study, we have investigated the regulatory role played by In1.1T/C (rs2280789) polymorphism of CCL5 and -135G/A (rs56061981) polymorphism of CXCL10 gene on intracellular CCL5 and CXCL10 expression in T
Singh, Brijendra +2 more
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Genetic variations in chemokine genes influence the chemoattractive properties of T cells which may be associated with outcome of infections. In present study, we have investigated the regulatory role played by In1.1T/C (rs2280789) polymorphism of CCL5 and -135G/A (rs56061981) polymorphism of CXCL10 gene on intracellular CCL5 and CXCL10 expression in T
Singh, Brijendra +2 more
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2022
Objective: Chemokine proteins are significantly effective in inflammation and immunity. Chemokines are from the family of the chemokine proteins and they organise the leukocyte trafficking through the formation of chemotactic activity in the cells that express the appropriate chemokine receptors.
ŞENTÜRK ÇİFTÇİ, Hayriye +4 more
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Objective: Chemokine proteins are significantly effective in inflammation and immunity. Chemokines are from the family of the chemokine proteins and they organise the leukocyte trafficking through the formation of chemotactic activity in the cells that express the appropriate chemokine receptors.
ŞENTÜRK ÇİFTÇİ, Hayriye +4 more
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells
Cancer Cell, 2022Emeric Limagne +2 more
exaly
What Is Currently Known about the Role of CXCL10 in SARS-CoV-2 Infection?
International Journal of Molecular Sciences, 2022Monika Gudowska-Sawczuk +2 more
exaly