Results 301 to 310 of about 76,809 (334)

CXCL12-G801A基因多态性在非小细胞肺癌中的表达及发病风险相关性研究

, 2017
黄佳滨, 隋小芳, 王凤玲, 袁博洋, 刘影, 范巧菊   +5 more
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A cytokine receptor-targeting chimera toolbox for expanding extracellular targeted protein degradation. [PDF]

Proc Natl Acad Sci U S A
Kumru K, Yao Z, Holmes BB, Zhao F, Zhang Y, Ferrara E, Peters-Clarke TM, Leung KK, Wells JA.   +8 more
europepmc   +1 more source

Author Correction: Activation of mTORC1 in subchondral bone preosteoblasts promotes osteoarthritis by stimulating bone sclerosis and secretion of CXCL12. [PDF]

Bone Res
Lin C, Liu L, Zeng C, Cui ZK, Chen Y, Lai P, Wang H, Shao Y, Zhang H, Zhang R, Zhao C, Fang H, Cai D, Bai X.   +13 more
europepmc   +1 more source

Chemokines and their receptors in oral squamous cell carcinoma: mechanisms, clinical significance, and therapeutic implications. [PDF]

Front Immunol
Li D, Chen S, Ji J, Wang Z, Zhou H, Liao Z, Tang Q.   +6 more
europepmc   +1 more source

Upexpression of BHLHE40 in gastric epithelial cells increases CXCL12 production through interaction with p-STAT3 in Helicobacter pylori-associated gastritis

Teng, Yong-Sheng, Zhao, YL, Li, MS, Liu, YG, Cheng, P, Lv, YP, Mao, FY, Chen, Weisan, Yang, SM, Hao, CJ, Peng, LS, Zhang, JY, Zhang, WJ, Zou, QM, Zhuang, Y   +14 more
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CXCL12-CXCL4 heterodimerization prevents CXCL12-driven breast cancer cell migration

Cellular Signalling, 2020
Despite improvements in cancer early detection and treatment, metastatic breast cancer remains deadly. Current therapeutic approaches have very limited efficacy in patients with triple negative breast cancer. Among the many mechanisms associated that contribute to cancer progression, signaling through the CXCL12-CXCR4 is an essential step in cancer ...
Khanh T.P. Nguyen, Lawrence J. Druhan, Belinda R. Avalos, Li Zhai, Lubica Rauova, Irina V. Nesmelova, Didier Dréau   +6 more
openaire   +2 more sources

CXCL12: Role in neuroinflammation

The International Journal of Biochemistry & Cell Biology, 2012
CXCL12, also known as SDF-1 (stromal cell derived factor-1) is a small protein that belongs to the chemokine family, whose members have a crucial role in directing cell migration. CXCL12 has an essential role in neural and vascular development, hematopoiesis and in immunity. It acts through two receptors, CXCR4 and CXCR7.
Timotijević, Gordana S, Mostarica-Stojković, Marija B, Miljković, Đorđe   +2 more
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CXCL12 Signaling in the Tumor Microenvironment

2021
Tumor microenvironment (TME) is the local environment of tumor, composed of tumor cells and blood vessels, extracellular matrix (ECM), immune cells, and metabolic and signaling molecules. Chemokines and their receptors play a fundamental role in the crosstalk between tumor cells and TME, regulating tumor-related angiogenesis, specific leukocyte ...
Luigi, Portella, Anna Maria, Bello, Stefania, Scala   +2 more
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CXCL12 in control of neuroinflammation

Immunologic Research, 2012
Inflammation within the central nervous system (CNS) is strictly controlled and if possible prevented. Such a tight control is necessary due to high sensitivity of nervous tissue to mechanical and biochemical consequences of inflammation. Still, neuroinflammation is a typical feature of a chronic, inflammatory, demyelinating disease multiple sclerosis (
Momčilović, Miljana, Mostarica-Stojković, Marija B, Miljković, Đorđe   +2 more
openaire   +3 more sources