Results 181 to 190 of about 34,241 (258)

Glucocorticoids induce a phagocytic C1Q+ macrophage phenotype primed for IFNγ-dependent CXCL9 secretion. [PDF]

Sci Rep
Triebig AS, Maier T, Schwarzlmueller P, Atici S, Kirmaier ME, Chortis V, Borges KS, Breault DT, Ribeiro C, Gottschlich A, Landwehr LS, Bechmann N, Peitzsch M, Paramasivam N, Theurich S, Fröhling S, Glimm H, Hübschmann D, Fassnacht M, Reincke M, Friedmann-Angeli JP, Weigand I, Kroiss M.   +22 more
europepmc   +1 more source

449 CXCL9 as a biomarker for disease activity in patients with morphea [PDF]

Journal of Investigative Dermatology, 2018
S. Florez-Pollack, J.C. O'Brien, H.T. Jacobe   +2 more
openaire   +1 more source

Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang, Laurie Brenchley, Teresa Greenwell‐Wild, Vasileios Ionas Theofilou, Timothy G. Myers, Chi A. Ma, Katherine Howe, Stefania Pittaluga, Steven M. Holland, Niki M. Moutsopoulos, David Fraser, Gulbu Uzel   +11 more
wiley   +1 more source

Understanding the Molecular Landscape of Alopecia Areata: Key Genes, Regulatory Networks, and Therapeutic Targets

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Introduction Alopecia areata (AA) is an autoimmune disorder characterized by hair loss due to immune‐mediated destruction of hair follicles. The polygenic nature of AA, influenced by genetic and environmental factors, complicates its pathogenesis.
Ahmed Ibrahim AbdElneam, Mohammed Saleh Al‐Dhubaibi, Saleh Salem Bahaj, Ghada Farouk Mohammed, Lina Mohammed Atef   +4 more
wiley   +1 more source

Integrated Single-Cell and Spatial Analysis Reveals Context-Dependent Myeloid-T Cell Interactions in Response to Immune Checkpoint Blockade in Head and Neck Cancer. [PDF]

Clin Cancer Res
Golfinos-Owens AE, Lozar T, Khatri P, Johns ED, Hu R, Harari PM, Lambert PF, Fitzpatrick MB, Dinh HQ.   +8 more
europepmc   +1 more source

Multiomics Identification and Validation of an Integrin–Extracellular Matrix Network Driving Respiratory Syncytial Virus‐Induced Lung Injury and Repair

MedComm, Volume 7, Issue 7, July 2026.
This graphical abstract depicts the dynamic progression from acute lung inflammation to fibrotic repair following RSV infection. Multiomics analysis uncovers a central regulatory network coordinating key pathways including coagulation, extracellular matrix deposition, integrin signaling, and cytoskeletal reorganization.
Lili Zhou, Hua Guo, Xiaofeng Yu, Yu Ran, Ruiqi Liu, Jiali Zhu, Ran Li, Jie Xu, Leshi Chen, Yongliang Zhu, Long Zhang, Zhenjiang Bai, Fangfang Zhou   +12 more
wiley   +1 more source

Artemisinin-Related Therapeutic Strategies for Autoimmune Thyroiditis: Chemokine-Receptor Networks, Spatial Thyroid Biology, and Molecular Mechanisms. [PDF]

Drug Des Devel Ther
Sun Y, Yang X, Zhu Q, Yang R.
europepmc   +1 more source

RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment

MedComm, Volume 7, Issue 7, July 2026.
Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li, Yating Sun, Shuibin Lin, Quan Yuan   +3 more
wiley   +1 more source

CXCL9 is silenced in metastasis to the bone in humans with prostate cancer.

Prostate cancer is among the most frequent cancers diagnosed in males and the most common site of distant metastasis in humans with prostate cancer is the skeletal system (bones). We measured total transcription in the pelvic metastases of humans with metastatic prostate cancer to identify gene expression changes important for metastasis to the ...
openaire   +2 more sources

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source