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Editorial: Community series in unraveling the molecular mechanisms of cytokine signaling in regulating inflammatory diseases, volume II. [PDF]
Zheng J, Mao H, Chong WP.
europepmc +1 more source
CXCL9 and CXCL10 Induce Expression of Nociceptive Ion Channels in Primary Sensory Neurons in Models of HIV-Associated Distal Sensory Polyneuropathy. [PDF]
Warfield R +9 more
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Highly Sensitive Immuno-CRISPR Assay for CXCL9 Detection
CRISPR-based detection of target DNA or RNA exploits a dual function, including target sequence-specific recognition followed by trans-cleavage activity of a collateral ssDNA linker between a fluorophore (F) and a quencher (Q), which amplifies a fluorescent signal upon cleavage.
Inseon Lee +4 more
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CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy
Chemokines are proteins which induce chemotaxis, promote differentiation of immune cells, and cause tissue extravasation. Given these properties, their role in anti-tumor immune response in the cancer environment is of great interest.
Madiha Naseem +2 more
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CXCL9 and CXCL10 bring the heat to tumors
Science Immunology, 2022CXCL9 and CXCL10 can be produced by antigen-presenting cells (dendritic cells or macrophages) and by tumor cells. Hoch et al. demonstrated that CXCL9 and CXCL10 co-localize with LAG3 + T cells expressing CCL4 or CXCL13 and contribute to the generation
Robin Reschke, Thomas F. Gajewski
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Tumour-infiltrating lymphocytes (TILs) are associated with improved survival in several epithelial cancers. The two chemokines CXCL9 and CXCL10 facilitate chemotactic recruitment of TILs, and their intratumoral accumulation is a conceivable way to ...
Holger Bronger +2 more
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