Results 21 to 30 of about 28,744 (150)

Computational Study of C-X-C Chemokine Receptor (CXCR)3 Binding with Its Natural Agonists Chemokine (C-X-C Motif) Ligand (CXCL)9, 10 and 11 and with Synthetic Antagonists: Insights of Receptor Activation towards Drug Design for Vitiligo

Molecules, 2020
Vitiligo is a hypopigmentary skin pathology resulting from the death of melanocytes due to the activity of CD8+ cytotoxic lymphocytes and overexpression of chemokines.
Giovanny Aguilera-Durán, Antonio Romo-Mancillas   +1 more
doaj   +1 more source

CXCR3 Expression and Genome-Wide 3′ Splice Site Selection in the TCGA Breast Cancer Cohort

Life, 2021
CXCR3 is a chemokine receptor with two well-characterized isoforms that have unique, context-dependent roles: CXCR3-A and CXCR3-B, which are produced through alternative 3′ splice site selection (A3SS).
Lauren A. Levesque, Scott Roy, Nicole Salazar   +2 more
doaj   +1 more source

Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers.

PLoS ONE, 2022
PurposePeripheral T cell CXCR3 expression has been found uniquely lower in patients having neovascular age-related macular degeneration (nAMD) than in healthy individuals. The CXCR3-axis has been shown to have angiostatic and antifibrotic properties.
Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen   +4 more
doaj   +2 more sources

CXCL10 and CXCR3 in the Trigeminal Ganglion Contribute to Trigeminal Neuropathic Pain in Mice

Journal of Pain Research, 2021
Yuan-Yuan Ju,1,2 Ming Jiang,2 Feifei Xu,1,3 Dongqin Wang,1,3 Bixiao Ding,1,3 Ling-Jie Ma,2 Hao Wu1 1Department of Otolaryngology, Head, and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, People’s Republic of China ...
Ju YY, Jiang M, Xu F, Wang D, Ding B, Ma LJ, Wu H   +6 more
doaj  

CXCR3 Provides a Competitive Advantage for Retention of Mycobacterium tuberculosis-Specific Tissue-Resident Memory T Cells Following a Mucosal Tuberculosis Vaccine

Vaccines, 2023
Mycobacterium tuberculosis is a major human pathogen, and new vaccines are needed to prevent transmission. Mucosal vaccination may confer protection against M. tuberculosis by stimulating tissue-resident memory (TRM) CD4+ T cells in the lungs.
Ellis Armitage, Diana Quan, Manuela Flórido, Umaimainthan Palendira, James A. Triccas, Warwick J. Britton   +5 more
doaj   +1 more source

Inducible Costimulator-C-X-C Motif Chemokine Receptor 3 Signaling is Involved in Chronic Obstructive Pulmonary Disease Pathogenesis

International Journal of COPD, 2022
Dan-Yang Li,1,* Long Chen,1,* Shuai-Ying Miao,1,2 Mei Zhou,1 Jiang-Hua Wu,1 Sheng-Wen Sun,1 Lan-Lan Liu,1 Chang Qi,1 Xian-Zhi Xiong1 1Department of Respiratory and Critical Care Medicine, Key Laboratory of Pulmonary Diseases of National Health ...
Li DY, Chen L, Miao SY, Zhou M, Wu JH, Sun SW, Liu LL, Qi C, Xiong XZ   +8 more
doaj  

ANALYSIS OF T-HELPER SUBSETS OF PERIPHERAL BLOOD OF PATIENTS WITH CHRONIC HEPATITIS C EXPRESSING CHEMOKINE RECEPTORS CXCR3 AND CCR6 AND ACTIVATION MARKERS CD38 AND HLA-DR

Инфекция и иммунитет, 2014
. In case of hepatitis C the adequate adaptive immune response depends on T-helper lymphocyte subsets and recruiting specific T cells in the site of infection.
D. S. Elezov, I. V. Kudryavtsev, N. A. Arsentieva, A. V. Semenov, E. V. Esaulenko, V. V. Basina, Areg A. Totolian   +6 more
doaj   +1 more source

ROLE OF CXCR3 CHEMOKINE RECEPTOR AND ITS LIGANDS IN CERTAIN DISEASES

Медицинская иммунология, 2019
Chemokines are a special family of cytokines whose main function is to control cell migration; they are key players in the innate and adaptive immune responses.
N. A. Arsentieva, A. V. Semenov, D. A. Zhebrun, E. V. Vasilyeva, Areg A. Totolian   +4 more
doaj   +1 more source

Transcriptomic Analysis of the Effects of Chemokine Receptor CXCR3 Deficiency on Immune Responses in the Mouse Brain during Toxoplasma gondii Infection

Microorganisms, 2021
The obligate intracellular parasite Toxoplasma gondii infects warm-blooded animals, including humans. We previously revealed through a whole-brain transcriptome analysis that infection with T.
Kousuke Umeda, Youta Goto, Kenichi Watanabe, Nanako Ushio, Ragab M. Fereig, Fumiaki Ihara, Sachi Tanaka, Yutaka Suzuki, Yoshifumi Nishikawa   +8 more
doaj   +1 more source

CXCR3 CHEMOKINE RECEPTOR EXPRESSION ON PERIPHERAL BLOOD B-CELL SUBSETS IN PATIENTS WITH CHRONIC HEPATITIS C

Медицинская иммунология, 2014
. Present study was aimed to perform a quantitative determination of B lymphocyte subpopulations, i.e., B1, B2, memory B cells and CXCR3-positive B cells in peripheral blood of nineteen patients with chronic hepatitis C (HCV) and thirty-two healthy blood
N. A. Arsentieva, I. V. Kudryavtsev, D. S. Elezov, A. V. Semenov, E. V. Esaulenko, V. V. Basina, Areg A. Totolian   +6 more
doaj   +1 more source