Results 1 to 10 of about 62,416 (259)

Firing up the cold tumors by targeting Vps34

OncoImmunology, 2020
Cancer immunotherapy based on anti-PD-1/PD-L1 blockade is particularly effective in responding to patients with hot tumors. These tumors are characterized by the accumulation of proinflammatory cytokines and T cell infiltration.
Bassam Janji, Meriem Hasmim, Santiago Parpal, Guy Berchem, Muhammad Zaeem Noman   +4 more
doaj   +1 more source

CXCR3 chemokine receptor ligands in sarcoidosis

Медицинская иммунология, 2021
Sarcoidosis is a polysystemic inflammatory disease of unknown etiology, morphologically related to the group of granulomatosis, with heterogeneous clinical manifestations and outcomes.
N. M. Lazareva, O. P. Baranova, I. V. Kudryavtsev, N. A. Arsentieva, N. E. Liubimova, T. P. Ses’, M. M. Ilkovich, Areg A. Totolian   +7 more
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MAPK signaling regulates the efficacy of chemoimmunotherapy

Molecular & Cellular Oncology, 2022
Resistance to chemoimmunotherapy is a major issue for cancer care. We recently unravelled the role of mitogen-activated protein kinase (MAPK) to limit the antitumor efficacy of such combination.
François Ghiringhelli
doaj   +1 more source

IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist

Kidney & Blood Pressure Research, 2020
Introduction: Various viruses including a novel coronavirus (SARS-CoV-2) can infect the kidney. When viruses invade the glomeruli from the bloodstream, glomerular endothelial cells (GECs) initiate the innate immune reactions.
Tadaatsu Imaizumi, Shun Hashimoto, Riko Sato, Hidenori Umetsu, Tomomi Aizawa, Shojiro Watanabe, Shogo Kawaguchi, Tomoh Matsumiya, Kazuhiko Seya, Jiangli Ding, Hiroshi Tanaka   +10 more
doaj   +1 more source

Porcine Endogenous Retrovirus Induces CXCL10 in Human Monocytes and Monocyte-Derived Primary Cells

Intervirology, 2022
Introduction: Pigs are suitable donor species for xenotransplantation and biological materials from these animals are used for this purpose for many years.
Hussein Al-Shehabi, Norbert Bannert
doaj   +1 more source

Sitagliptin: a potential drug for the treatment of COVID-19?

Acta Pharmaceutica, 2021
Recently, an outbreak of a fatal coronavirus, SARS-CoV-2, has emerged from China and is rapidly spreading worldwide. Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis.
Bardaweel Sanaa K., Hajjo Rima, Sabbah Dima A.   +2 more
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The effect of transplantation of cultured autologous melanocytes on CXCL9, CXCL10 and CXCL11 expressions in vitiligo

Indian Journal of Dermatology, 2023
Background: Vitiligo is an acquired chronic autoimmune skin disorder with an estimated prevalence of 1% worldwide. The CD8+ T-cell-mediated chemokines such as CXCR3, CXCL9 and CXCL10 are the non-specific action immunomodulators that are responsible for ...
Chen Xu, Zixian Lei, Li Wang, Hongjuan Wang, Wen Hu, Halina Hairuola, Xiaojing Kang   +6 more
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Effect of azithromycin on migration of peripheral blood NK cells from patients with chronic obstructive pulmonary disease

Медицинская иммунология, 2023
Currently, no drugs have been identified that could slow progression of chronic obstructive pulmonary disease (COPD), or have a significant impact on patient mortality.
A. G. Kadushkin, A. D. Tahanovich, L. V. Movchan, M. M. Zafranskaya, T. V. Shman   +4 more
doaj   +1 more source

CXCL10 May Be Responsible for Susceptibility to Pulmonary Embolism in COVID-19 Patients

Journal of Inflammation Research, 2023
Yingli Liu,1 Dan Si,2 Pingping Bai,3 Li Zhu,4 Lili Zhang,1 Qi Chen,5 Yong Qi6 1Department of Pulmonary and Critical Care Medicine, Zhengzhou University People’s Hospital, Henan Provincial People’s Hospital, Zhengzhou, Henan, 450003, People’s Republic of ...
Liu Y, Si D, Bai P, Zhu L, Zhang L, Chen Q, Qi Y   +6 more
doaj  

Development of a machine learning-based signature utilizing inflammatory response genes for predicting prognosis and immune microenvironment in ovarian cancer

Open Medicine, 2023
Ovarian cancer (OC) represents a significant health challenge, characterized by a particularly unfavorable prognosis for affected women. Accumulating evidence supports the notion that inflammation-related factors impacting the normal ovarian epithelium ...
Dong Li, Qian Ya-ping, Li Shu-xiu, Pan Hao   +3 more
doaj   +1 more source