Results 191 to 200 of about 142,759 (329)

439. CXCR4 and CCR5 shRNA Transgenic Macrophages Are Functionally Normal and Resist HIV-1 Infection [PDF]

, 2005

openalex   +1 more source

Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy [PDF]

, 2023
Daria Klusa, Fabian Lohaus, André Franken, Marian Baumbach, Monica Cojoc, Paul Dowling, Annett Linge, Anne Offermann, Steffen Löck, Dejan Hušman, Mahdi Rivandi, Bernhard Polzer, Vera Freytag, Tobias Lange, Hans Neubauer, Michael Kücken, Sven Perner, Tobias Hölscher, Anna Dubrovska, Mechthild Krause, Ina Kurth, Michaël Baumann, Claudia Peitzsch   +22 more
openalex   +1 more source

Hypoxia regulates Th17/Treg balance by altering chromatin accessibility and gene expression

The FEBS Journal, EarlyView.
T‐cell differentiation into Th17 or iTreg cells is key to inflammation control. Integrated RNA‐seq and ATAC‐seq analyses reveal that hypoxia induces more extensive gene expression changes in iTreg cells. Elevated levels of Hif1a and Stat3, along with increased accessibility to key transcription factor motifs, may predispose these cells toward ...
Mariana Cázares‐Olivera, Shiyang Song, Sofia Ylinen, Talha Qureshi, Bin Li, Zhi Chen   +5 more
wiley   +1 more source

Exploring the impact of baseline and on‐treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study

HIV Medicine, EarlyView.
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
M. Gartland, X. Wang, Q. Liao, B. Li, F. Du, M. Krystal, A. R. Tenorio, A. Pierce, J. R. Castillo‐Mancilla   +8 more
wiley   +1 more source

Identification of Matrine as a Novel Regulator of the CXCR4 Signaling Axis in Tumor Cells [PDF]

, 2020
Young Yun Jung, Jae‐Young Um, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Alan Prem Kumar, Kwang Seok Ahn   +6 more
openalex   +1 more source

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, EarlyView.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

Impact of neuroendocrine neoplasm-specific systemic treatments on expression and function of CXCR4 in neuroendocrine tumor cells. [PDF]

Sci Rep
Däubler C, Böttcher C, Landwehr LS, Meining A, Michalski K, Reiter F, Werner RA, Hartrampf P, Rogoll D, Weich A.   +9 more
europepmc   +1 more source

Differential Expression of CXCL12 and CXCR4 During Human Fetal Neural Progenitor Cell Differentiation

, 2007
Hui Peng, Ryan Kolb, Jane E. Kennedy, Jialin Zheng   +3 more
openalex   +2 more sources

Comparison of the Response to the CXCR4 Antagonist AMD3100 During Development of Retinal Organoids Derived from ES Cells and of Zebrafish Retina

, 2021
Yihui Wu, Jin Qiu, Shuilian Chen, Xi Chen, Jing Zhang, Jiejie Zhuang, Sian Liu, Meng Yang, Pan Zhou, Haoting Chen, Jian Ge, Keming Yu, Jing Zhuang   +12 more
openalex   +1 more source

scRNA‐Seq reveals anti‐lymphoma immune responses in mogamulizumab‐associated skin eruptions

Journal of the European Academy of Dermatology and Venereology, EarlyView.
CCR4 was expressed in malignant clones and regulatory T cells in untreated CTCL, that were decreased in MAR. Malignant clones in MAR showed a silenced phenotype with decreases in central memory markers SELL and CCR7, and GTP‐binding member GIMAP7 and upregulation of MMP2 inhibitor TIMP2 and tumour suppressor gene RUNX3.
Shannon Meledathu, Agata Kurowski, Malini P. Naidu, Jonas Adalsteinsson, Shane A. Meehan, Natalia Alkon, Lauren R. Port, Sumanth Chennareddy, Emry R. Cohenour, Grace Christensen, Jonah Shulman, Nicholas Gulati, Constanze Jonak, Patrick M. Brunner   +13 more
wiley   +1 more source