Results 21 to 30 of about 18,162 (295)

Cyanocobalamin-Modified Colistin–Hyaluronan Conjugates: Synthesis and Bioactivity

International Journal of Molecular Sciences, 2023
Polymeric drug delivery systems enhance the biopharmaceutical properties of antibiotics by increasing their bioavailability, providing programmable and controlled-release properties, and reducing toxicity.
N. Dubashynskaya, Anton N. Bokatyi, T. Sall, Tatiana S. Egorova, Y. Nashchekina, Y. Dubrovskii, E. Murashko, E. Vlasova, E. Demyanova, Y. Skorik   +9 more
semanticscholar   +1 more source

The Preparation and Evaluation of Cyanocobalamin Mucoadhesive Sublingual Tablets

Pharmaceuticals, 2023
Cobalamin (vitamin B12), an essential vitamin with low oral bioavailability, plays a vital role in cellular functions. This research aimed to enhance the absorption of vitamin B12 using sublingual mucoadhesive tablets by increasing the residence time of ...
Anwar Ma’ali, Hani A Naseef, Moammal Qurt, A. Abukhalil, Abdullah K Rabba, Israr N. Sabri   +5 more
semanticscholar   +1 more source

Effects of cyanocobalamin and its combination with morphine on neuropathic rats and the relationship between these effects and thrombospondin-4 expression

The Korean Journal of Pain, 2022
Background Thrombospondin-4 (TSP4) upregulates in the spinal cord following peripheral nerve injury and contributes to the development of neuropathic pain (NP).
Neslihan Düzenli, Sibel Ülker, Gülgün Şengül, Buse Kayhan, Aytül Önal   +4 more
semanticscholar   +1 more source

Safety and efficacy of a feed additive consisting of vitamin B12 (cyanocobalamin) produced by fermentation with Ensifer adhaerens CGMCC 19596 for all animal species (Hebei Huarong Pharmaceutical Co. ltd)

EFSA Journal, 2023
The vitamin B12 (in the form of cyanocobalamin) under assessment is produced by fermentation with Ensifer adhaerens CGMCC 19596 and it is intended to be used as a nutritional additive for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Pier Sandro Cocconcelli, Rosella Brozzi, Jaume Galobart, Orsolya Holczknecht, Mateo Innocenti, Paola Manini, Elisa Pettenati, Jordi Tarrés‐Call, Maria Vittoria Vettori, Anita Radovnikovic   +27 more
doaj   +1 more source

Cyanocobalamin prevents cardiomyopathy in type 1 diabetes by modulating oxidative stress and DNMT-SOCS1/3-IGF-1 signaling

Communications Biology, 2021
Patients with long-standing diabetes have a high risk for cardiac complications that is exacerbated by increased reactive oxygen species (ROS) production.
M. Kakoki, Purushotham V. Ramanathan, J. Hagaman, Ruriko Grant, Jennifer C. Wilder, Joan M. Taylor, J. Charles Jennette, O. Smithies, Nobuyo Maeda-Smithies   +8 more
semanticscholar   +1 more source

Prevention of Post-Resection Acute Liver Failure by Various Methods of Cyanocobalamin Administration in the Experiment [PDF]

International Journal of Biomedicine, 2020
Background: Surgical treatment of massive hepatic formations is an acute problem of operative hepatology, often being the only way to increase the life expectancy of patients.
Anastasiya Yu. Laptiyova, Alexandr A. Andreev, Аlexandr А. Glukhov, Dmitry A. Atiakshin, Anton P. Ostroushko, Sergey N. Boyev, Tatyana G. Nikishina, Elena V. Mikulich, Pyotr I. Koshelev, Ekaterina A. Andreeva   +9 more
doaj   +1 more source

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E

Microorganisms, 2023
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute ...
Yassmin Moatasim, Omnia Kutkat, Ahmed M. Osman, Mokhtar R. Gomaa, Faten Okda, Mohamed El Sayes, Mina Nabil Kamel, Mohamed Gaballah, Ahmed Mostafa, Rabeh El-Shesheny, Ghazi Kayali, Mohamed A. Ali, Ahmed Kandeil   +12 more
doaj   +1 more source

Sublingual methylcobalamin treatment is as effective as intramuscular and peroral cyanocobalamin in children age 0–3 years

Hematology, 2021
Purpose: Vitamin B12 deficiency is a cause of preventable growth and developmental retardation in children. In this respect, alternative methods such as oral and sublingual treatments are being tried. We aimed to compare the efficacy of oral, sublingual,
Betül Orhan Kılıç, Serhat Kılıç, Elif Şahin Eroğlu, Eylem Gül, Fatma Burcu Belen Apak   +4 more
semanticscholar   +1 more source

Influence of storage conditions and packaging of fortified wheat flour on microbial load and stability of folate and vitamin B12

Food Chemistry: X, 2020
Flour fortification with folic acid (FA) is implemented in many countries, and the fortification of flour with vitamin B12 has been planned. However, vitamins losses can occur during storage.
Youna M. Hemery, Laura Fontan, Arnaud Laillou, Vincent Jallier, Regina Moench-Pfanner, Sylvie Avallone, Jacques Berger   +6 more
doaj   +1 more source

Combined biotin, folic acid, and vitamin B12 supplementation given during the transition period to dairy cows: Part II. Effects on energy balance and fatty acid composition of colostrum and milk

Journal of Dairy Science, 2022
: Biotin (B8), folate (B9), and vitamin B12 (B12) are involved in several metabolic reactions related to energy metabolism. We hypothesized that a low supply of one of these vitamins during the transition period would impair metabolic status.
M. Duplessis, R. Gervais, H. Lapierre, C.L. Girard   +3 more
doaj   +1 more source