Results 121 to 130 of about 8,652,661 (302)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
COMPOSITIONAL AND DRAMATURGICAL ELEMENTS IN GHEORGHE NEAGA’S SUITE FOR STRING QUARTET [PDF]
Opuses in the suite genre represent a significant part in Gheorghe Neaga’s instrumental chamber repertoire, but also keep an important place in the gold heritage of the autochthonous chamber music.
Chiciuc Natalia
doaj
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The intelligence cycle is a set of processes used to provide useful information for decision-making. The cycle consists of several processes. The related counter-intelligence area is tasked with preventing information efforts from others.
Sfetcu, Nicolae
core
The operation of the γ-aminobutyrate bypath of the tricarboxylic acid cycle in brain tissue in vitro
Ben Hammond +4 more
openalex +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Coordination of membrane phospholipid synthesis with the cell cycle.
Suzanne Jackowski
openalex +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
L’utilisation du matériel pédagogique en classe multiâge
Cet article présente les résultats d’une recherche menée auprès d’enseignants titulaires de classes multiâges de la région du Saguenay―Lac-Saint-Jean. Il présente un nouveau regard sur l’utilisation du matériel pédagogique qui se fait dans le contexte ...
Nicole Monney, Christine Couture
doaj

