Results 221 to 230 of about 17,158 (246)

Cyclic ADP-Ribose and Vasomotor Response

2002
Vascular smooth muscle (VSM) usually exists in a partially contracted state, from which it can contract further or relax in response to different physiological or pathological stimulations. This contracted state of blood vessels and their contracting and relaxing response to stimuli are often referred to as “vascular tone” and “vasomotor response ...
Pin-Lan Li, Ai-Ping Zou, William B. Campbell   +2 more
openaire   +1 more source

Cyclic ADP-Ribose and Calcium Signalling

1998
It is over 100 years since calcium was first implied as an intracellular regulator in heart by Ringer (1882). Since then its universal role as a regulator has become a cornerstone of cell physiology (Campbell 1983), and much progress has been made in our understanding of cellular calcium homeostasis and the way in which cellular stimuli are transduced ...
A. Galione, H. L. Wilson
openaire   +1 more source

Calcium signaling by cyclic ADP-ribose and NAADP

Cell Biochemistry and Biophysics, 1998
Ca2+ mobilization as a signaling mechanism has been placed on center stage with the discovery of the first Ca2+ messenger, inositol trisphosphate (IP3). This article focuses on two new Ca2+ release activators, which mobilize internal Ca2+ stores via mechanisms totally independent of IP3.
openaire   +3 more sources

Cyclic ADP-Ribose: Metabolism and Calcium Mobilizing Function

1994
Publisher Summary This chapter describes the discovery of cyclic adenosine diphosphate–ribose (cADPR) as a novel endogenous Ca 2+ -mobilizing agent, and the way by which it fulfills most of the criteria necessary for it to be considered a second messenger. The enzymatic pathways for the synthesis and degradation of the metabolite are also summarized.
H C, Lee, A, Galione, T F, Walseth
openaire   +2 more sources

[27] Preparation of cyclic ADP-ribose antagonists and caged cyclic ADP-ribose

1997
Timothy F. Walseth, Robert Aarhus, Mary E. Gurnack, Long Wong, Hans-Georg A. Breitinger, Kyle R. Gee, Hon Cheung Lee   +6 more
openaire   +1 more source

Cyclic ADP-ribose and NAADP

2003
Antony Galione, Grant C. Churchill
openaire   +1 more source

Cyclic ADP-Ribose in β Cells

Science, 1993
Md. Shahidul Islam, Olof Larsson, Per-Olof Berggren   +2 more
openaire   +1 more source

Poly(ADP-Ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic

Ca-A Cancer Journal for Clinicians, 2011
Timothy A Yap, Shahneen Sandhu, Craig P Carden   +2 more
exaly  

Cyclic ADP-Ribose and NAADP

2002
openaire   +2 more sources

Cyclic ADP-ribose

Journal of Molecular Medicine, 2000
Andreas H Guse, Guse Andreas H
exaly