Mitochondrial-Endothelial Crosstalk in Cardiometabolic Disease: Mechanisms and Translational Opportunities in the Multi-omics Era. [PDF]
Rev Cardiovasc MedLiu D +6 more
europepmc +1 more source
Multi-omics analysis reveals Protein Kinase A-associated regulatory remodeling during adaptation of Trichoderma reesei to lignocellulosic substrate. [PDF]
World J Microbiol BiotechnolZenaide-Neto H +9 more
europepmc +1 more source
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Cyclic AMP-dependent protein kinase of Neurosporacrassa
Biochemical and Biophysical Research Communications, 1980Abstract Neurospora crassa was surveyed for cyclic AMP-dependent protein kinase activity. Two peaks (I and II) of protein kinase activity were demonstrated by DEAE-cellulose chromatography of wild type Neurospora extracts. Peak I was stimulated by cyclic AMP, eluted below 60 mM NaCl and had high activity using histone H2B as substrate ...
P A, Powers, M L, Pall
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Protein Phosphorylation Catalyzed by Cyclic AMP-Dependent and Cyclic GMP-Dependent Protein Kinases
Annual Review of Pharmacology and Toxicology, 1980D B Glass, E G Krebs
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A cyclic AMP dependent protein kinase in Dictyosteliumdiscoideum
Biochemical and Biophysical Research Communications, 1982Abstract A cyclic AMP-dependent protein kinase was found to appear during the time course of development of Dictyostelium discoideum . No cyclic AMP dependency was observed at any stage of development in crude 110,000 X G soluble extracts. After partial purification, however, extracts from post-aggregation stages contained enzyme that was ...
C L, Rutherford +3 more
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Phosphorylation of Tau by Cyclic-AMP-Dependent Protein Kinase
Dementia and Geriatric Cognitive Disorders, 1993Alzheimer's disease paired helical filaments contain abnormally phosphorylated tau (PHF-tau) which has reduced electrophoretic mobility on sodium dodecyl sulphate polyacrylamide electrophoresis. We have investigated the effects of cyclic-AMP-dependent protein kinase (PKA) on recombinant human tau isoforms and two recombinant tau fragments.
J, Robertson +6 more
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Activation of cyclic AMP-dependent protein kinase in macrophages
Biochemical and Biophysical Research Communications, 1984The activity of cyclic AMP-dependent protein kinase (cyclic AMP-PK) was significantly higher (P less than 0.001) in thioglycollate-elicited than in resident rat peritoneal macrophages. The activity ratio of the enzyme (its activity in the absence of added cyclic AMP divided by that in the presence of 5 microM cyclic AMP) was similar in the two cell ...
N H, Hunt +4 more
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Inhibition of cyclic AMP-dependent protein kinase by curcumin
Phytochemistry, 1996Curcumin [diferuloylmethane; 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione], a major bioactive secondary metabolite found in the rhizomes of turmeric (Curcuma longa), is an inhibitor of Ca(2+)- and phospholipid-dependent protein kinase C (PKC) and of the catalytic subunit (cAK) of cyclic AMP-dependent protein kinase (IC50 values 15 and 4 ...
M, Hasmeda, G M, Polya
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Synthetic substrate for cyclic AMP-dependent protein kinase
Nature, 1975MOST hormones and neurotransmitters are thought to stimulate the synthesis of adenosine 3′,5′-cyclic monophosphate (cyclic AMP) which in turn activates protein kinases1. On activation, the protein kinases transfer the terminal phosphate group of ATP to serine or threonine residues in enzymic or membrane proteins involved in metabolic regulation ...
P, Daile, P R, Carnegie, J D, Young
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