Results 21 to 30 of about 64,058 (295)

Homologous and Heterologous Phosphorylations of Human Histamine H1 Receptor in Intact Cells

open access: yesJournal of Pharmacological Sciences, 2004
Homologous and heterologous phosphorylations of histamine H1 receptor (H1R) in intact cells were investigated using Chinese hamster ovary cells stably co-expressing c-myctagged human histamine H1 and muscarinic M3 receptors. Increase in histamine-induced
Katsuhiro Miyoshi   +3 more
doaj   +1 more source

Cyclic nucleotide dependent dephosphorylation of regulator of G-protein signaling 18 in human platelets.

open access: yesPLoS ONE, 2013
Regulator of G-protein signaling 18 (RGS18) is a GTPase-activating protein that turns off Gq signaling in platelets. RGS18 is regulated by binding to the adaptor protein 14-3-3 via phosphorylated serine residues S49 and S218 on RGS18.
Kristina Gegenbauer   +2 more
doaj   +1 more source

Regulation of the G2/M Transition in Rodent Oocytes [PDF]

open access: yes, 2010
Regulation of maturation in meiotically competent mammalian oocytes is a complex process involving the carefully coordinated exchange of signals between the somatic and germ cell compartments of the ovarian follicle via paracrine and cell–cell coupling ...
Downs, Stephen
core   +2 more sources

Dunce mutants of Drosophila melanogaster: mutants defective in the cyclic AMP phosphodiesterase enzyme system [PDF]

open access: yes, 1981
The cyclic AMP and cyclic GMP phosphodiesterase activities present in flies of six mutant strains of the dunce gene and in the parent wild- type strains are characterized. All of the mutants exhibit aberrant cyclic AMP metabolism.
Davis, Ronald L., Kiger, John A., Jr.
core   +1 more source

Zonisamide Ameliorates Cognitive Impairment by Inhibiting ER Stress in a Mouse Model of Type 2 Diabetes Mellitus

open access: yesFrontiers in Aging Neuroscience, 2020
Type 2 diabetes mellitus (T2DM) increases the risk of Alzheimer’s disease (AD)-like dementia and pathology. Endoplasmic reticulum stress (ERS) plays a key role in the development of cognitive impairment in T2DM. Zonisamide (ZNS) was found to suppress ERS-
Yong-Xiang He   +7 more
doaj   +1 more source

Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]

open access: yes, 2012
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal   +94 more
core   +2 more sources

Molecular Mechanism of Neuronal Plasticity: Induction and Maintenance of Long-Term Potentiation in the Hippocampus

open access: yesJournal of Pharmacological Sciences, 2006
.: Recent studies have demonstrated that activation of enzymes can be observed in living cells in response to stimulation with neurotransmitters, hormones, growth factors, and so forth.
Eishichi Miyamoto
doaj   +1 more source

A Cyclic AMP-Dependent Protein Kinase of the Bovine Pineal Gland [PDF]

open access: yesProceedings of the National Academy of Sciences, 1971
A protein kinase that is dependent on cAMP was found to be present in significant amounts in rat and bovine pineal glands. This enzyme system was isolated from bovine pineal glands and shown to consist of two proteins, a kinase and a cAMP-binding protein.
J A, Fontana, W, Lovenberg
openaire   +2 more sources

The AGC Kinase SsAgc1 Regulates Sporisorium scitamineum Mating/Filamentation and Pathogenicity

open access: yesmSphere, 2019
Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite ...
Yixu Wang   +7 more
doaj   +1 more source

Porcine oocyte maturation in vitro : role of cAMP and oocyte-secreted factors: a practical approach [PDF]

open access: yes, 2016
Polyspermy or the penetration of more than one sperm cell remains a problem during porcine in vitro fertilization (IVF). After in vitro culture of porcine zygotes, only a low percentage of blastocysts develop and their quality is inferior to that of in ...
Appeltant, Ruth   +4 more
core   +2 more sources

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