Results 21 to 30 of about 32,015 (246)
Journal of Pharmacological Sciences, 2006 .: Recent studies have demonstrated that activation of enzymes can be observed in living cells in response to stimulation with neurotransmitters, hormones, growth factors, and so forth.
Eishichi Miyamoto
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The AGC Kinase SsAgc1 Regulates
mSphere, 2019 Sporisorium scitamineum is the fungal pathogen causing severe sugarcane smut disease that leads to massive economic losses globally. S. scitamineum invades host cane by dikaryotic hyphae, formed after sexual mating of two haploid sporidia of opposite ...
Yixu Wang +7 more
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A Cyclic AMP-Dependent Protein Kinase of the Bovine Pineal Gland [PDF]
Proceedings of the National Academy of Sciences, 1971 A protein kinase that is dependent on cAMP was found to be present in significant amounts in rat and bovine pineal glands. This enzyme system was isolated from bovine pineal glands and shown to consist of two proteins, a kinase and a cAMP-binding protein.
J A, Fontana, W, Lovenberg
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Memorias do Instituto Oswaldo Cruz, 2004 Trypanosoma evansi contains protein kinases capable of phosphorylating endogenous substrates with apparent molecular masses in the range between 20 and 205 kDa.
José Manuel Galán-Caridad +4 more
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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
Cell Reports, 2020 Summary: Stimulator of Interferon Genes (STING) is a critical component of host innate immune defense but can contribute to chronic autoimmune or autoinflammatory disease.
Katherine R. Balka +15 more
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Engineering a bioluminescent indicator for cyclic AMP-dependent protein kinase [PDF]
Biochemical Journal, 1991 cDNA coding for the luciferase in the firefly Photinus pyralis was amplified in vitro to generate cyclic AMP-dependent protein kinase phosphorylation sites. The DNA was transcribed and translated to generate light-emitting protein. A valine at position 217 was mutated to arginine to generate a site RRFS and the heptapeptide kemptide, the ...
G B, Sala-Newby, A K, Campbell
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Journal of Pharmacological Sciences, 2004 To clarify heterologous regulation of a receptor is important in considering medication. Histamine constricts the airway smooth muscle through the action to the H1 receptor (H1R), which contributes to asthma.
Nozomi Kawakami +3 more
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Phosphorylation of β-Catenin by Cyclic AMP-dependent Protein Kinase [PDF]
Journal of Biological Chemistry, 2006 Beta-catenin is a signaling molecule that promotes cell proliferation by the induction of gene transcription through the activation of T-cell factor (TCF)/lymphoid enhancer factor (LEF) transcription factors. The canonical mechanism of the regulation of beta-catenin involves its phosphorylation by casein kinase 1 at the Ser-45 site and by glycogen ...
Sebastien, Taurin +4 more
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Molecular Plant-Microbe Interactions, 2004 Sclerotial development is fundamental to the disease cycle of the omnivorous broad host range fungal phytopathogen Sclerotinia sclerotiorum. We have isolated a highly conserved homolog of ERK-type mitogen-activated protein kinases (MAPKs) from S ...
Changbin Chen +4 more
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PPP6C Negatively Regulates STING-Dependent Innate Immune Responses
mBio, 2020 Stimulator of interferon genes (STING) is an essential adaptor protein of the innate DNA-sensing signaling pathway, which recognizes genomic DNA from invading pathogens to establish antiviral responses in host cells.
Guoxin Ni +6 more
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