6-Bromo-2-methylsulfanyl-1,3-benzothiazole
The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski +2 more
doaj +1 more source
Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor [PDF]
Koji Ozasa +9 more
openalex +1 more source
Dysfunctional Light-Evoked Regulation of cAMP in Photoreceptors and Abnormal Retinal Adaptation in Mice Lacking Dopamine D4 Receptors [PDF]
Dopamine is a retinal neuromodulator that has been implicated in many aspects of retinal physiology. Photoreceptor cells express dopamine D4 receptors that regulate cAMP metabolism.
Grandy, David K. +6 more
core +1 more source
Bipolar Hydrogen Production by Hybrid Water Electrolysis
This review focuses on the recent advances in uniqueness bipolar H2 production from the oxidation of representative small molecules, including 5‐hydroxymethylfurfural, formaldehyde, alcohols, and N‐heterocycle amides. The target electrocatalysts and the underlying mechanisms are discussed in respect to specific substrate oxidation.
Jiachen Li +5 more
wiley +1 more source
Pentacarbonyl(imidazolidine-2-thione-κS)tungsten(0)
In the title complex, [W(C3H6N2S)(CO)5], the W atom displays an octahedral coordination with five CO molecules and an imidazolidine-2-thione molecule. The W(CO)5 unit is coordinated by the cyclic thione ligand through a W—S dative bond.
Salah Merniz +4 more
doaj +1 more source
The Global Regulatory Cyclic AMP Receptor Protein (CRP) Controls Multifactorial Fluoroquinolone Susceptibility in Salmonella enterica Serovar Typhimurium [PDF]
Stefani C. Kary +5 more
openalex +1 more source
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Bis(4-carbamoylpiperidinium) biphenyl-4,4′-disulfonate
In the title isonipecotamide salt 2C6H13N2O+·C12H8O6S22−, the asymmetric unit comprises one biphenyl-4,4′-disulfonate dianion which lies across a crystallographic inversion centre and another in a general position [dihedral ...
Graham Smith +2 more
doaj +1 more source
Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility. [PDF]
Ronald E. Weishaar +3 more
openalex +1 more source
SLC19A1 transports immunoreactive cyclic dinucleotides. [PDF]
The accumulation of DNA in the cytosol serves as a key immunostimulatory signal associated with infections, cancer and genomic damage1,2. Cytosolic DNA triggers immune responses by activating the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon ...
Corn, Jacob E +10 more
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