Bis(4-carbamoylpiperidinium) biphenyl-4,4′-disulfonate
In the title isonipecotamide salt 2C6H13N2O+·C12H8O6S22−, the asymmetric unit comprises one biphenyl-4,4′-disulfonate dianion which lies across a crystallographic inversion centre and another in a general position [dihedral ...
Graham Smith+2 more
doaj +1 more source
SGAC: A Graph Neural Network Framework for Imbalanced and Structure-Aware AMP Classification [PDF]
Classifying antimicrobial peptides(AMPs) from the vast array of peptides mined from metagenomic sequencing data is a significant approach to addressing the issue of antibiotic resistance. However, current AMP classification methods, primarily relying on sequence-based data, neglect the spatial structure of peptides, thereby limiting the accurate ...
arxiv
Cofactor Fingerprinting with STD NMR to Characterize Proteins of Unknown Function: Identification of a Rare cCMP Cofactor Preference [PDF]
Proteomics efforts have created a need for better strategies to functionally categorize newly discovered proteins. To this end, we have employed saturation transfer difference NMR with pools of closely related cofactors, to determine cofactor preferences.
Sem, Daniel, Yao, Huili
core +1 more source
The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference! [PDF]
Kinetoplastids are unicellular, eukaryotic, flagellated protozoans containing the eponymous kinetoplast. Within this order, the family of trypanosomatids are responsible for some of the most serious human diseases, including Chagas disease (Trypanosoma ...
De Koning, Harry P.+2 more
core +1 more source
Growth regulatory effects of cyclic AMP and polyamine depletion are dissociable in cultured mouse lymphoma cells. [PDF]
Treatment of mouse lymphoma S49 cells with D,L-alpha-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, depleted cellular polyamine levels and stopped cell growth. The cells were arrested predominantly in G1.
Coffino, P, Marton, LJ, McConlogue, LC
core
Genome-wide screening reveals metabolic regulation of stop-codon readthrough by cyclic AMP. [PDF]
Lyu Z+7 more
europepmc +1 more source
Unifying AMP Algorithms for Rotationally-Invariant Models [PDF]
This paper presents a unified framework for constructing Approximate Message Passing (AMP) algorithms for rotationally-invariant models. By employing a general iterative algorithm template and reducing it to long-memory Orthogonal AMP (OAMP), we systematically derive the correct Onsager terms of AMP algorithms.
arxiv
The present study was undertaken to determine the relationship between the antilipolytic and lipolytic effects of insulin on hormone-stimulated lipolysis and the mechanisms of these reactions.
K.S. Desai, K.C. Li, A. Angel
doaj
Fast and spectrally accurate construction of adaptive diagonal basis sets for electronic structure [PDF]
In this article, we combine the periodic sinc basis set with a curvilinear coordinate system for electronic structure calculations. This extension allows for variable resolution across the computational domain, with higher resolution close to the nuclei and lower resolution in the inter-atomic regions.
arxiv
Concise Derivation of Complex Bayesian Approximate Message Passing via Expectation Propagation [PDF]
In this paper, we address the problem of recovering complex-valued signals from a set of complex-valued linear measurements. Approximate message passing (AMP) is one state-of-the-art algorithm to recover real-valued sparse signals. However, the extension of AMP to complex-valued case is nontrivial and no detailed and rigorous derivation has been ...
arxiv