Results 61 to 70 of about 30,015 (162)

Cyclic‐AMP Response Element Binding Protein [PDF]

, 2008
  +4 more sources

Inhibiting H3K27 Demethylases Downregulates CREB‐CREBBP, Overcoming Resistance in Relapsed Acute Lymphoblastic Leukemia

Cancer Medicine
Background CREB binding protein (CREBBP) is a key epigenetic regulator, altered in a fifth of relapsed cases of acute lymphoblastic leukemia (ALL). Selectively targeting epigenetic signaling may be an effective novel therapeutic approach to overcome drug
Juan Lazaro‐Navarro, Clara Alcon, Mathurin Dorel, Lina Alasfar, Lorenz Bastian, Claudia Baldus, Kathy Astrahantseff, Marie‐Laure Yaspo, Joan Montero, Cornelia Eckert   +9 more
doaj   +1 more source

SPTLC3 regulates plasma membrane sphingolipid composition to facilitate hepatic gluconeogenesis

Cell Reports
Summary: SPTLC3, an inducible subunit of the serine palmitoyltransferase (SPT) complex, causes production of alternative sphingoid bases, including a 16-carbon dihydrosphingosine, whose biological function is only beginning to emerge.
David Montefusco, Maryam Jamil, Daniel Canals, Siri Saligrama, Yang Yue, Jeremy Allegood, L. Ashley Cowart   +6 more
doaj   +1 more source

The Transcription Factor Creb is Involved in Sorafenib-Inhibited Renal Cancer Cell Proliferation, Migration and Invasion

Acta Pharmaceutica, 2018
Our previous reports showed that the cyclic-AMP-response element-binding protein (CREB) served as a proto-oncogene in the process of tumorigenesis and mediated the growth and metastatic activity of renal cancer cells.
Huang Shuaishuai, Cui Pinger, Lin Shuangxia, Yao Xuping, Wang Xue, Ren Yu, Weng Guobin   +6 more
doaj   +1 more source

cAMP/PKA/CREB/GLT1 signaling involved in the antidepressant-like effects of phosphodiesterase 4D inhibitor (GEBR-7b) in rats

Neuropsychiatric Disease and Treatment, 2016
Xu Liu,1,2,* Haibiao Guo,1,* Mohammad Daud SOM Sayed,3,4,* Yang Lu,3,4,* Ting Yang,5,* Dongsheng Zhou,6 Zhongming Chen,6 Haitao Wang,1 Chuang Wang,3,4 Jiangping Xu1 1Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical ...
Liu X, Guo H, Sayed MDSM, Lu Y, Yang T, Zhou D, Chen Z, Wang H, Wang C, Xu J   +9 more
doaj  

Regulation of Cyclic AMP-Response Element Binding Protein Zhangfei (CREBZF) Expression by Estrogen in Mouse Uterus. [PDF]

Dev Reprod, 2018
Jang H.
europepmc   +1 more source

Cyclic AMP-Responsive Element-Binding Protein 1 [PDF]

, 2020
openaire   +1 more source

Melatonin ameliorates cuprizone-induced reduction of hippocampal neurogenesis, brain-derived neurotrophic factor, and phosphorylation of cyclic AMP response element-binding protein in the mouse dentate gyrus. [PDF]

Brain Behav, 2019
Kim W, Hahn KR, Jung HY, Kwon HJ, Nam SM, Kim JW, Park JH, Yoo DY, Kim DW, Won MH, Yoon YS, Hwang IK.   +11 more
europepmc   +1 more source

Cyclic AMP-Responsive Element-Binding Protein 5 [PDF]

, 2020
openaire   +1 more source

Differential Expression of Cyclic AMP-Response Element Binding Protein Zhangfei (CREBZF) in the Mouse Testis during Postnatal Development. [PDF]

Dev Reprod, 2018
Jang H.
europepmc   +1 more source