Results 61 to 70 of about 20,142 (297)

Slope stability in slightly fissured claystones and marls [PDF]

open access: yes, 2015
The final publication is available at Springer via http://dx.doi.org/10.1007/s10346-014-0526-5The paper deals with the behavior of some characteristic soft rocks found in the Iberian Peninsula.
Alonso Pérez de Agreda, Eduardo   +1 more
core   +2 more sources

Study on the Cyclic Impact Mechanical Characteristics of Coal under Confining Pressure

open access: yesACS Omega
Coal damage accumulation and strength deterioration caused by mining-induced disturbances in deep mines are among the factors influencing the occurrence of dynamic disasters such as rock bursts. To study the mechanical deformation and failure characteristics of coal masses under both cyclic impact and confining pressure, SHPB experiments were performed
He Yongliang, Sun Liying, Xing Xuegang
openaire   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Hydromechanical Coupling Characteristics of the Fractured Sandstone under Cyclic Loading-Unloading

open access: yesGeofluids, 2020
The mechanical and hydraulic properties of rock mass play a crucial role in underground engineering. To study the effect of hydraulic pressure, confining pressure, and axial cyclic loading-unloading on variation of the deformation and permeability in ...
Tong Zhang   +5 more
doaj   +1 more source

Strain Limits for Concrete Filled Steel Tubes in AASHTO Seismic Provisions [PDF]

open access: yes, 2013
INE/AUTC 13 ...
King Brown, Nicole   +2 more
core  

Behavior of confined granular beds under cyclic thermal loading

open access: yes, 2019
We investigate the mechanical behavior of a confined granular packing of irregular polyhedral particles under repeated heating and cooling cycles by means of numerical simulations with the Non-Smooth Contact Dynamics method.
Giacomazzi, Elena   +5 more
core   +1 more source

Effect of confining pressure on the degradation of ballast under cyclic loading

open access: yesGéotechnique, 2005
Traditional railway foundations or substructures have become increasingly overloaded in recent years due to the introduction of faster and heavier trains. A lack of substructure re-engineering has resulted in maintenance cycles becoming more frequent and increasingly expensive.
Indraratna, Buddhima   +2 more
openaire   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Effects of grain size distribution on the initial strain shear modulus of calcareous sand [PDF]

open access: yes, 2015
The soil’s small strain shear modulus, Gmax or G0, is applied in dynamic behavior analyses and is correlated to other soil properties (density and void ratio) for predicting soil dynamic behavior under seismic loadings such as earthquakes, machinery or ...
Haegeman, Wim   +4 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

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