Results 111 to 120 of about 485,549 (166)

Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide. [PDF]

Sci Rep, 2016
Omura H, Oikawa D, Nakane T, Kato M, Ishii R, Ishitani R, Tokunaga F, Nureki O.   +7 more
europepmc   +1 more source

Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon. [PDF]

Immunity, 2019
Li X, Deng M, Petrucelli AS, Zhu C, Mo J, Zhang L, Tam JW, Ariel P, Zhao B, Zhang S, Ke H, Li P, Dokholyan NV, Duncan JA, Ting JP.   +14 more
europepmc   +1 more source

The Complement Anaphylatoxins C5a and C3a Suppress IFN-β Production in Response to Listeria monocytogenes by Inhibition of the Cyclic Dinucleotide-Activated Cytosolic Surveillance Pathway. [PDF]

J Immunol, 2017
Mueller-Ortiz SL, Calame DG, Shenoi N, Li YD, Wetsel RA.   +4 more
europepmc   +1 more source

Convergent evolution of viral nucleases targeting cyclic dinucleotides. [PDF]

PLoS Pathog
Li Z, Zhang L.
europepmc   +1 more source

Current Perspectives on STING Agonists for Anticancer Drug Development. [PDF]

Chem Biol Drug Des
Kahvecioglu Cicek D.
europepmc   +1 more source

The Great Potential of the Cluster of Differentiation 38 (CD38) Inhibitors in the Treatment of Cancer and Age-Related Metabolic dysfunction. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source

Recent Advances in the Molecular Mechanisms of Bacterial Anti-Phage Defence Systems. [PDF]

Microb Biotechnol
Brüssow H.
europepmc   +1 more source

Inhibition by ATP regulates the activity of a CBASS anti-phage nucleotide cyclase. [PDF]

Biochem J
Gaskell-Mew L, McQuarrie S, McMahon SA, Wotherspoon P, Graham S, Gloster TM, White MF.   +6 more
europepmc   +1 more source

Type B Lactic Acidosis: Diagnosis, Etiology and Treatment - An Educational Review. [PDF]

Cardiol Res
Cardenas Fimbres JA, Cardenas Fimbres JM, Stewart C, Tobias JD.   +3 more
europepmc   +1 more source

Enzymatic synthesis of cyclic dinucleotide analogs by a promiscuous cyclic-AMP-GMP synthetase and analysis of cyclic dinucleotide responsive riboswitches [PDF]

Nucleic Acids Research, 2018
Cyclic dinucleotides are second messenger molecules produced by both prokaryotes and eukaryotes in response to external stimuli. In bacteria, these molecules bind to RNA riboswitches and several protein receptors ultimately leading to phenotypic changes such as biofilm formation, ion transport and secretion of virulence factors.
Scott Strobel, Katherine Launer-Felty
exaly   +4 more sources