Results 1 to 10 of about 18,412 (234)

Efficient production of a cyclic dipeptide (cyclo-TA) using heterologous expression system of filamentous fungus Aspergillus oryzae [PDF]

Microbial Cell Factories, 2022
Background Cyclic dipeptides are an important class of natural products owing to their structural diversity and biological activities. In fungi, the cyclo-ring system is formed through the condensation of two α-amino acids via non-ribosomal peptide ...
Jianzhao Qi, Haiyan Han, Dan Sui, Shengnan Tan, Changli Liu, Pengchao Wang, Chunliang Xie, Xuekui Xia, Jin-ming Gao, Chengwei Liu   +9 more
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Limosilactobacillus (Lactobacillus) fermentum ALAL020, a Probiotic Candidate Bacterium, Produces a Cyclic Dipeptide That Suppresses the Periodontal Pathogens Porphyromonas gingivalis and Prevotella intermedia [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
Periodontal disease develops as a result of oral microbiota in dysbiosis, followed by the growth of periodontal pathogens such as Porphyromonas gingivalis and Prevotella intermedia.
Tomomi Kawai, Tomoko Ohshima, Takeshi Tanaka, Satoshi Ikawa, Atsushi Tani, Naoya Inazumi, Ryoichi Shin, Yukie Itoh, Karen Meyer, Nobuko Maeda   +9 more
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Isolation, Characterization and Chemical Synthesis of Large Spectrum Antimicrobial Cyclic Dipeptide (l-leu-l-pro) from Streptomyces misionensis V16R3Y1 Bacteria Extracts. A Novel ¹H NMR Metabolomic Approach [PDF]

Antibiotics, 2020
Streptomyces is the most frequently described genus of Actinomycetes, a producer of biologically active secondary metabolites. Indeed, the Streptomyces species produces about 70% of antibiotics and 60% of antifungal molecules used in agriculture.
Ilhem Saadouli, Imène Zendah El Euch, Emna Trabelsi, Amor Mosbah, Alaeddine Redissi, Raoudha Ferjani, Imene Fhoula, Ameur Cherif, Jean-Marc Sabatier, Norbert Sewald, Hadda-Imene Ouzari   +10 more
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Untargeted metabolomics identifies a bacterial cyclic dipeptide that induces resistance to a rust fungus of beans [PDF]

Scientific Reports
Genistein and daidzein are isoflavonoid phytoalexins that increase rapidly during bean hypersensitive immunity to Pseudomonas savastanoi pv. phaseolicola. To understand how genistein and daidzein affect P. savastanoi pv.
Bret Cooper, Ronghui Yang, Kimberly B. Campbell   +2 more
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High-tolerance crystalline hydrogels formed from self-assembling cyclic dipeptide [PDF]

Beilstein Journal of Nanotechnology, 2019
Peptide-based supramolecular hydrogels, as a new type of biological nanoarchitectonic structure, hold great promise for a wide range of biomedical and nanotechnological applications, such as tissue engineering, drug delivery, and electronic and photonic ...
Yongcai You, Ruirui Xing, Qianli Zou, Feng Shi, Xuehai Yan   +4 more
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Isolation of Petrocidin A, a New Cytotoxic Cyclic Dipeptide from the Marine Sponge-Derived Bacterium Streptomyces sp. SBT348 [PDF]

Marine Drugs, 2017
A new cyclic dipeptide, petrocidin A (1), along with three known compounds—2,3-dihydroxybenzoic acid (2), 2,3-dihydroxybenzamide (3), and maltol (4)—were isolated from the solid culture of Streptomyces sp. SBT348. The strain Streptomyces sp.
Cheng Cheng, Eman M. Othman, Helga Stopper, RuAngelie Edrada-Ebel, Ute Hentschel, Usama Ramadan Abdelmohsen   +5 more
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Exploring Sources, Biological Functions, and Potential Applications of the Ubiquitous Marine Cyclic Dipeptide: A Concise Review of Cyclic Glycine-Proline [PDF]

Marine Drugs
Cyclic glycine-proline (cGP), a prevalent marine cyclic dipeptide, possesses a distinct pyrrolidine-2,5-dione scaffold, which contributes to the chemical diversity and broad bioactivities of cGP.
Lei Hu, Jing Lin, Fei Qin, Li Xu, Lianzhong Luo   +4 more
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The Structural Characterisation and DFT-Aided Interpretation of Vibrational Spectra for Cyclo(l-Cys-d-Cys) Cyclic Dipeptide in a Solid State [PDF]

Molecules, 2023
Cyclic dipeptides with two intramolecular peptide bonds forming a six-membered 2,5-diketopiperazine ring are gaining significant attention due to their biological and chemical properties. Small changes in the local geometry of such molecules (from cis to
Marcin Witkowski, Damian Trzybiński, Sylwia Pawlędzio, Krzysztof Woźniak, Wojciech Dzwolak, Agata Królikowska   +5 more
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Small cyclic dipeptide produced by Lactobacillus rhamnosus with anti-biofilm properties against Streptococcus mutans biofilm [PDF]

Biofilm
The human oral cavity harbors many bacterial species collectively termed the oral microbiome and is integral for maintaining oral health. Dysbiosis of oral microbiota leads to common oral diseases, including dental caries, gingivitis, and periodontitis ...
Rashmi Niranjan, Sachin Patil, Amrita Dubey, Bimlesh Lochab, Richa Priyadarshini   +4 more
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Insights into the Bioactivities and Mechanism of Action of the Microbial Diketopiperazine Cyclic Dipeptide Cyclo(L-leucyl-L-prolyl) [PDF]

Marine Drugs
Diketopiperazines (DKPs) are biologically important cyclic dipeptides widespread in nature, associated primarily with microorganisms. This is the case for the 2,5-DKP derivative cyclo(L-Leu-L-Pro) (cLP), also known as gancidin W or PPDHMP, identified ...
Christian Bailly
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