Results 151 to 160 of about 18,412 (234)

Probiotic-Driven Metabolic Transformation in Dark Tea: Enhanced Bioactives and Gut Microbiota Modulation Underlie Its Alleviation Effect Against Constipation

open access: yesFoods
Constipation is a widespread gastrointestinal condition with complex causes and limited therapeutic efficacy of current treatments. Probiotics and natural-function foods like dark tea (DT) have emerged as promising alternatives.
Yufeng Xie   +6 more
doaj   +1 more source

From Solution to Surface: How the Catalytic Environment Modulates Peptide Bond Cleavage by Metal‐Oxo Cluster Nanozymes

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Comparison of homogeneous Hf12(sol) and heterogeneous Hf12(precip) metal‐oxo clusters enables investigation of how solubility influences nanozymatic reactivity and selectivity toward proteolysis, without introducing confounding factors from differences in cluster identity.
Kilian Declerck   +7 more
wiley   +1 more source

Photoisomerization in Cyclic Dipeptide Derivatives: Photoswitchable Supramolecular Hydrogels and the Discovery of Hemipiperazine Photoswitches

open access: yesChemPhotoChem, Volume 10, Issue 3, March 2026.
Photoswitchable cyclic dipeptides (CDPs) can be used to prepare hydrogels that reversibly dissipate upon irradiation, or to photomodulate the development of living organisms. We report here applications and perspectives for CDPs containing azobenzene photoswitches or newly discovered hemipiperazine photoswitches in smart materials and biological ...
Zbigniew L. Pianowski
wiley   +1 more source

Metaproteome Analysis of Short‐Term Thermal Stress in Three Sympatric Coral Species Reveals Divergent Host Responses

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
Short‐term thermal stress triggers distinct molecular responses in three sympatric coral species with contrasting thermal resilience. Proteomic and metabolomic profiling reveal both species‐specific and limited shared pathways underlying these stress responses.
Shrinivas Nandi   +5 more
wiley   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Biogenesis of Organelles and Membrane Proteins. [PDF]

open access: yes, 1988
Harmey, Matthew A.   +3 more
core   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

open access: yesNew Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov   +16 more
wiley   +1 more source

Oligoglyceric acid synthesis by autocondensation of glyceroyl thioester [PDF]

open access: yes
The autocondensation of the glyceroyl thioester, S-glyceroyl-ethane-thiol, yielded olioglyceric acid. The rates of autocondensation and hydrolysis of the thioester increased from pH 6.5 to pH 7.5 in 2,6-lutidine and imidazole buffers.
Weber, A. L.
core   +1 more source

Effect of α‐Hydrazino Acids on the Performance of H‐Pro–Pro‐Xaa Catalysts in the Conjugate Addition of Aldehydes to Nitroolefins

open access: yesChemistrySelect, Volume 11, Issue 11, 18 March 2026.
The tripeptide Pro‐Pro‐D‐hVal‐OMe, which lacks an acidic group, catalysed the conjugate addition of aldehydes to nitroolefins and afforded γ‐nitroaldehydes in 79–97% yield and 88:14–93:7 e.r. The proposed reaction mechanism relies on the active role of hydrazide NHβ or NHα protons in hydrogen bonding with the reacting species.
Ivona Banović   +2 more
wiley   +1 more source

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