Results 161 to 170 of about 18,412 (234)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Temporal Control Over Complex, Simple, and Multiphase Coacervates Using Ureolysis and Ammonium Carbonate Decomposition

open access: yesChemSystemsChem, Volume 8, Issue 2, March 2026.
A new strategy for temporal control over simple and complex coacervates is described here. The urea‐urease reaction results in the timed formation and/or destruction of complex coacervates after controllable delays. This strategy is easily adaptable to different time scales and polyelectrolyte pairs.
Shana Shirin Valapra   +4 more
wiley   +1 more source

Synthesis of dipeptide mimics based on amino phosphinate backbones and cyclic derivatives

open access: yesARKIVOC, 2015
Florian Rüping   +2 more
doaj   +1 more source

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

open access: yesAllergy, Volume 81, Issue 3, Page 884-901, March 2026.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat   +16 more
wiley   +1 more source

Crystal structure of plant γ‐glutamyl peptidase 1: implications for sulfur metabolism and secondary metabolite biosynthesis

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1400-1414, March 2026.
The crystal structures of Arabidopsis thaliana γ‐glutamyl peptidase 1 (GGP1), including the covalent intermediate state, were determined. GGP1 is involved in both glutathione degradation in the primary metabolism and glutathione conjugate processing in the secondary metabolism of glucosinolate and camalexin biosynthesis.
Kosei Sone   +7 more
wiley   +1 more source

How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley   +1 more source

Dynamic balance of myoplasmic energetics, redox state and protons in a fast‐twitch oxidative glycolytic skeletal muscle fibre

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 1840-1871, 1 March 2026.
Abstract figure legend We have developed a computational model of energy metabolism in fast‐twitch oxidative glycolytic muscle fibres. The model considers thermodynamically constrained enzyme kinetics derived from in vitro data and was validated against in vivo data from phosphorus magnetic resonance spectroscopy.
Jana Disch   +4 more
wiley   +1 more source

Characterization of the cyclic dipeptide cyclo(His-Pro) in Arabidopsis. [PDF]

open access: yesPlant Physiol
Minen RI   +14 more
europepmc   +1 more source

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