Results 31 to 40 of about 18,412 (234)

Purification and structure elucidation of three naturally bioactive molecules from the new terrestrial Streptomyces sp. TN17 strain [PDF]

, 2011
Thirty litres of fermentation broth was extracted from the newly isolated Streptomyces sp. strain TN17 and various separation and purification steps led to the isolation of three pure bioactive compounds (1–3).
Coppel, Yannick, Fourati Ben Fguira, Lilia, Lebrihi, Ahmed, Mathieu, Florence, Mellouli, Lofti, Smaoui, Slim   +5 more
core   +2 more sources

Proline-Based Cyclic Dipeptides from Korean Fermented Vegetable Kimchi and from Leuconostoc mesenteroides LBP-K06 Have Activities against Multidrug-Resistant Bacteria

Frontiers in Microbiology, 2017
Lactobacillus plantarum and Leuconostoc mesenteroides play a prominent role as functional starters and predominant isolates in the production of various types of antimicrobial compound-containing fermented foods, especially including kimchi.
Min-Kyu Kwak, Sa-Ouk Kang, Rui Liu, Andrew H. Kim   +3 more
doaj   +1 more source

Continual reproduction of self-assembling oligotriazole peptide nanomaterials. [PDF]

, 2017
Autocatalytic chemical reactions, whereby a molecule is able to catalyze its own formation from a set of precursors, mimic nature's ability to generate identical copies of relevant biomolecules, and are thought to have been crucial for the origin of life.
Brea, Roberto J, Devaraj, Neal K
core   +2 more sources

Identification of isomeric cyclo(leu-pro) produced by Pseudomonas sesami BC42 and its differential antifungal activities against Colletotrichum orbiculare

Frontiers in Microbiology, 2023
Pseudomonas spp. produce various antimicrobial substances, including cyclic peptides, which have been shown to suppress fungal pathogens. In a previous study, Pseudomonas sesami BC42 was selected to control anthracnose caused by Colletotrichum orbiculare
Jiwon Kim, Jiwon Kim, Jin-Cheol Kim, Mee Kyung Sang   +3 more
doaj   +1 more source

Explicit factorization of external coordinates in constrained Statistical Mechanics models [PDF]

, 2006
If a macromolecule is described by curvilinear coordinates or rigid constraints are imposed, the equilibrium probability density that must be sampled in Monte Carlo simulations includes the determinants of different mass-metric tensors.
Abagyan, Abagyan, Almarza, Alonso, Barron, Berendsen, Berendsen, Case, Chandler, Chass, Chen, Chen, Choi, Chun, Cramer, Császár, Den Otter, Dill, Dobson, Echenique, Echenique, Fixman, Fixman, Gō, Gō, Hansmann, He, Helfand, Hess, Jain, Keiderling, Klos, Levantino, Láng, Mantsch, Mazur, Morse, Nivón, Pasquali, Patriciu, Pear, Pelton, Perchak, Perczel, Plotkin, Rallison, Reich, Senderowitz, Shental-Benchor, Shimada, Smith, Sreerama, Taylor, Van Gunsteren, Van Kampen, Van Kampen, Vargas, Wilson, Yang, Yu, Zhou, Álvarez-Estrada, Álvarez-Estrada   +62 more
core   +3 more sources

Synthesis of leucine-based cyclic dipeptides

Proceedings of the National Academy of Sciences of Belarus, Chemical Series, 2020
3-benzyl-6-isobutylpiperazin-2,5-dione [cyclo(leucylphenylalanyl)], 3-isobutylpiperazin-2,5-dione [cyclo(-leucylglycyl)] and 3-(sec-butyl-)-6-isobutyl-piperazine-2,5-dione [cyclo(leucylisoleucine)] have been obtained by cyclization of methyl esters of tert-butyloxycarbonyl derivatives of dipeptides, for the synthesis of which both carbodiimide-promoted
V. A. Haidukevich, L. A. Popova, P. V. Kurman, V. A. Knizhnikov   +3 more
openaire   +2 more sources

Structure-Based Exploration of Cyclic Dipeptide Chitinase Inhibitors [PDF]

Journal of Medicinal Chemistry, 2004
Family 18 chitinases play an essential role in a range of pathogens and pests. Several inhibitors are known, including the potent inhibitors argadin and allosamidin, and the structures of these in complex with chitinases have been elucidated. Recent structural analysis has revealed that CI-4 [cyclo-(L-Arg-D-Pro)] inhibits family 18 chitinases by ...
Houston, Douglas R., Synstad, Bjørnar, Eijsink, Vincent G. H., Stark, Michael J. R., Eggleston, Ian M., van Aalten, Daan M. F.   +5 more
openaire   +3 more sources

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways

Pharmacological Research, 2022
Ischemic/reperfusion (IR) can cause adverse reactions including apoptosis, oxidative stress, and inflammation, but the existing therapeutic strategies have been limited.
Jiale Cai, Jiayin Liang, Yutong Zhang, Lin Shen, Huiting Lin, Tao Hu, Sikai Zhan, Meixia Xie, Shengwang Liang, Minghua Xian, Shumei Wang   +10 more
doaj   +1 more source

Solvent and thermal stability, and pH kinetics, of proline-specific dipeptidyl peptidase IV-like enzyme from bovine serum [PDF]

, 2007
Proline-specific dipeptidyl peptidase-like (DPP IV; EC 3.4.14.5) activity in bovine serum has attracted little attention despite its ready availability and the paucity of useful proline-cleaving enzymes.
Abbott, Barry, Brendan F. O’Connor, Buckley, Bušek, Chruscinska, Ciarán Ó’Fágáin, De Meester, Deborah M. Ruth, Demuth, Dixon, Duke-Cohan, Dunn, Durinx, Edens, Engel, Fersht, FitzGerald, Gonzalez, Gorren, Grasso, Jagath, Khmelnitsky, Kikkawa, Lambeir, Lee, Maes, Mentlein, Mittal, Ogino, Ohkubo, Ohnishi, O’Cuinn, Poltorak, Poltorak, Rasmussen, Sears, Sentandreu, Sheehan, Smith, Séamus J. Buckley, Trubetskoy, Yaron, Yoshimoto   +43 more
core   +1 more source

Rational and combinatorial tailoring of bioactive cyclic dipeptides [PDF]

Frontiers in Microbiology, 2015
Modified cyclic dipeptides represent a diverse family of microbial secondary metabolites. They display a broad variety of biological and pharmacological activities and have long been recognized as privileged structures with the ability to bind to a wide range of receptors.
Tobias Wolfgang Giessen, Tobias Wolfgang Giessen, Mohamed A. Marahiel   +2 more
openaire   +4 more sources