Results 31 to 40 of about 4,865 (234)
Frontiers in Bioengineering and Biotechnology, 2021 We previously determined that the cyclase inhibitor tripropylamine (TPA) significantly enhances lycopene accumulation in Blakeslea trispora. To elucidate the mechanism of TPA-enhanced lycopene accumulation, the untargeted metabolome of B.
Yanlong Wang +8 more
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Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides
Pharmaceutics, 2022 The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs.
Gzona Bajraktari-Sylejmani +5 more
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Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]
Zhongguo niangzaoIn this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
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Fragmentation of 2,5-diketopiperazine cyclic dipeptide ions
Technical Physics, 2022 The mechanism of radiation damage to 2,5-diketopiperazine (DKP, C4H6N2O2) molecules in the gas phase upon interaction with He2+ ions with an energy Ep = 4 keV/u has been investigated. The relative cross sections of various elementary processes occurring in single collisions of DKP with ions have been measured for the first time.
A. A. Basalaev +4 more
openaire +1 more source
Advances in research on chemical constituents and pharmacological effects of Paecilomyces hepiali
Food Science and Human Wellness, 2021 Paecilomyces hepiali is a fungus with edible and pharmaceutic value, isolated from Ophiocordyceps sinensis. Its main bioactive constituents contain alkaloids, cyclic dipeptides, steroids, organic acids, and polysaccharides.
Akang Dan +5 more
doaj +1 more source
Bioactivatable Pseudotripeptidization of Cyclic Dipeptides To Increase the Affinity toward Oligopeptide Transporter 1 for Enhanced Oral Absorption: An Application to Cyclo(l‑Hyp‑l‑Ser) (JBP485) [PDF]
, 2019 The cyclic dipeptides generally present lower affinity toward intestinal oligopeptide transporter 1 (PEPT1) than the linear dipeptides. JBP485 (cyclo(l-Hyp-l-Ser)) is a low-affinity substrate of PEPT1 with poor oral bioavailability.
Yan Gao (93649) +18 more
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An alternative approach to create N -substituted cyclic dipeptides [PDF]
, 2019 International audienceN-Modified peptide backbones are promising peptidomimetics which offer several advantages in terms of improved biological activity and stability. They further allow the development of novel functional materials.
Illy, Nicolas +5 more
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Interfacial supramolecular biomimetic epoxidation catalysed by cyclic dipeptides [PDF]
, 2016 We synthesised a library of cis- and trans-cyclic dipeptides and evaluated their efficacy as catalysts in the asymmetric Weitz-Scheffer epoxidation of trans-chalcone.
Patrick Lagüe (690115) +15 more
core +1 more source
Journal of Marine Science and Engineering, 2021 Marine actinomycetes are a potential source of a wide variety of bioactive natural products. Herein, four cyclic dipeptides, namely, cyclo(L-Val-L-Pro) (compound 1), cyclo(L-Pro-L-Leu) (compound 2), cyclo(L-Pro-L-Tyr) (compound 3) and cyclo(L-Pro-L-Phe) (
Wenzhi Yang +3 more
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Molecules, 2023 Cyclic dipeptides with two intramolecular peptide bonds forming a six-membered 2,5-diketopiperazine ring are gaining significant attention due to their biological and chemical properties. Small changes in the local geometry of such molecules (from cis to
Marcin Witkowski +5 more
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