Results 31 to 40 of about 464,022 (216)

Anti-oxidative stress mechanism of cyclic dipeptide in distiller's grains of strong-flavor Baijiu [PDF]

Zhongguo niangzao
In this study, the in vitro antioxidant activity of free peptides in distiller's grains of strong-flavor (Nongxiangxing) Baijiu was determined by measuring the free radical scavenging rate of 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH).
GUO Yan, LIAO Qinjian, ZHENG Jia, WANG Fang, YANG Hao, ZHOU Hanling, SU Jian
doaj   +1 more source

Enzymatical and microbial degradation of cyclic dipeptides (diketopiperazines). [PDF]

AMB Express, 2013
Diketopiperazines (DKPs) are cyclic dipeptides, representing an abundant class of biologically active natural compounds. Despite their widespread occurrence in nature, little is known about their degradation. In this study, the enzymatical and microbial cleavage of DKPs was investigated.
Perzborn M, Syldatk C, Rudat J.
europepmc   +6 more sources

Cyclic dipeptides and the human microbiome: Opportunities and challenges

Bioorganic & Medicinal Chemistry, 2023
Research into the human microbiome has implicated its constituents in a variety of non-communicable diseases, with certain microbes found to promote health and others leading to dysbiosis and pathogenesis.Microbes communicate and coordinate their behaviour through the secretion of small molecules, such as cyclic dipeptides (CDPs), into their ...
Ogilvie, Charlene Elizabeth, Melo Czekster, Clarissa   +1 more
openaire   +3 more sources

Advances in research on chemical constituents and pharmacological effects of Paecilomyces hepiali

Food Science and Human Wellness, 2021
Paecilomyces hepiali is a fungus with edible and pharmaceutic value, isolated from Ophiocordyceps sinensis. Its main bioactive constituents contain alkaloids, cyclic dipeptides, steroids, organic acids, and polysaccharides.
Akang Dan, Yujia Hu, Ruyan Chen, Xiangyang Lin, Yongqi Tian, Shaoyun Wang   +5 more
doaj   +1 more source

Photoelectron spectra and structures of three cyclic dipeptides: PhePhe, TyrPro and HisGly [PDF]

, 2012
We have investigated the electronic structure of three cyclic dipeptides: cyclo(Histidyl-Glycyl) (cHisGly), cyclo(Tyrosyl-Prolyl) (cTyrPro), and cyclo(Phenylalanyl-Phenylalanyl) (cPhePhe) in the vapor phase, by means of photoemission spectroscopy and ...
Feyer, V., Kevin C. Prince, Prince, K. C., Anoja P. Wickrama Arachchilage, Feng Wang, Wickrama Arachchilage, A.P., Vitaliy Feyer, Oksana Plekan, Wang, F., Plekan, O.   +9 more
core   +2 more sources

Fragmentation of 2,5-diketopiperazine cyclic dipeptide ions

Technical Physics, 2022
The mechanism of radiation damage to 2,5-diketopiperazine (DKP, C4H6N2O2) molecules in the gas phase upon interaction with He2+ ions with an energy Ep = 4 keV/u has been investigated. The relative cross sections of various elementary processes occurring in single collisions of DKP with ions have been measured for the first time.
A. A. Basalaev, V. V. Kuz’michev, M. N. Panov, A. V. Petrov, O. V. Smirnov   +4 more
openaire   +1 more source

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +2 more sources

Bioactivatable Pseudotripeptidization of Cyclic Dipeptides To Increase the Affinity toward Oligopeptide Transporter 1 for Enhanced Oral Absorption: An Application to Cyclo(l‑Hyp‑l‑Ser) (JBP485)

, 2019
The cyclic dipeptides generally present lower affinity toward intestinal oligopeptide transporter 1 (PEPT1) than the linear dipeptides. JBP485 (cyclo­(l-Hyp-l-Ser)) is a low-affinity substrate of PEPT1 with poor oral bioavailability.
Yan Gao (93649), Yongjun Wang (134570), Qiming Kan (4975997), Jiangnan Zhang (1793173), Jian Wang (5901), Yao Feng (780789), Qikun Jiang (3093126), Meiling Luo (670453), Gang Wang (36685), Kexin Liu (1547230), Changyuan Wang (672924), Yang Wang (5921), Tianhong Zhang (167831), Jin Sun (117866), Peiyue Tong (7339586), Mengchi Sun (2617605), Yiqin Lv (7339589), Zhonggui He (1329060), Linlin Cao (5942924)   +18 more
core   +5 more sources

Bioactive Secondary Metabolites from Marine Streptomyces griseorubens f8: Isolation, Identification and Biological Activity Assay

Journal of Marine Science and Engineering, 2021
Marine actinomycetes are a potential source of a wide variety of bioactive natural products. Herein, four cyclic dipeptides, namely, cyclo(L-Val-L-Pro) (compound 1), cyclo(L-Pro-L-Leu) (compound 2), cyclo(L-Pro-L-Tyr) (compound 3) and cyclo(L-Pro-L-Phe) (
Wenzhi Yang, Guangjie Liang, Yang Sun, Zhijin Gong   +3 more
doaj   +1 more source

The Structural Characterisation and DFT-Aided Interpretation of Vibrational Spectra for Cyclo(l-Cys-d-Cys) Cyclic Dipeptide in a Solid State

Molecules, 2023
Cyclic dipeptides with two intramolecular peptide bonds forming a six-membered 2,5-diketopiperazine ring are gaining significant attention due to their biological and chemical properties. Small changes in the local geometry of such molecules (from cis to
Marcin Witkowski, Damian Trzybiński, Sylwia Pawlędzio, Krzysztof Woźniak, Wojciech Dzwolak, Agata Królikowska   +5 more
doaj   +1 more source