Results 21 to 30 of about 464,022 (216)
Identification of Cyclic Dipeptides from Escherichia coli as New Antimicrobial Agents against Ralstonia Solanacearum [PDF]
Molecules, 2018 Ralstonia solanacearum is a causative agent of bacterial wilt in many important crops throughout the world. How to control bacterial wilt caused by R. solanacearum is a major problem in agriculture.
Shihao Song +7 more
doaj +2 more sources
Macromolecular Materials and EngineeringAmphiphilic cyclic dipeptides are efficient supramolecular hydrogelators. They can be combined with molecular photoswitches to produce light‐responsive soft materials, which can be applied in controlled drug delivery. Here it is reported that an arginine‐
Angelika Seliwjorstow +4 more
doaj +2 more sources
Protein synthesis with conformationally constrained cyclic dipeptides. [PDF]
Bioorg Med Chem, 2020 We have synthesized several conformationally constrained dipeptide analogues as possible substrates for incorporation into proteins. These have included three cyclic dipeptides formed from Boc derivatives of 2,4-diaminobutyric acid, ornithine and lysine, having 5-, 6-, and 7-membered lactam rings, respectively.
Zhang C, Bai X, Dedkova LM, Hecht SM.
europepmc +4 more sources
Frontiers in Cell and Developmental Biology, 2022 Proline:arginine (PR) poly-dipeptides from the GGGGCC repeat expansion in C9orf72 have cytotoxicity and bind intermediate filaments (IFs). However, it remains unknown how PR poly-dipeptides affect cytoskeletal organization and focal adhesion (FA ...
Tomo Shiota +13 more
doaj +1 more source
Active site remodelling of a cyclodipeptide synthase redefines substrate scope
Communications Chemistry, 2022 Cyclodipeptide synthases (CDPSs) generate a wide range of cyclic dipeptides using aminoacylated tRNAs as substrates, however the substrate selection mechanism is not yet known.
Emmajay Sutherland +2 more
doaj +1 more source
Cyclic dipeptides and their self-assembling properties [PDF]
, 2017 Over recent years, cyclic dipeptides, or 2,5-diketopiperazines, have found numerous applications in nanotechnology, such as biological drug delivery. Reasons for this include their ease of synthesis and numerous intrinsic properties. One such property is
Balangtaa, Jacob
core +4 more sources
Microbial Cell Factories, 2022 Background Cyclic dipeptides are an important class of natural products owing to their structural diversity and biological activities. In fungi, the cyclo-ring system is formed through the condensation of two α-amino acids via non-ribosomal peptide ...
Jianzhao Qi +9 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 We previously determined that the cyclase inhibitor tripropylamine (TPA) significantly enhances lycopene accumulation in Blakeslea trispora. To elucidate the mechanism of TPA-enhanced lycopene accumulation, the untargeted metabolome of B.
Yanlong Wang +8 more
doaj +1 more source
Evaluation of PepT1 (SLC15A1) Substrate Characteristics of Therapeutic Cyclic Peptides
Pharmaceutics, 2022 The human peptide transporter hPepT1 (SLC15A1), physiologically transporting dipeptides and tripeptides generated during food digestion, also plays a role in the uptake of small bioactive peptides and peptide-like drugs.
Gzona Bajraktari-Sylejmani +5 more
doaj +1 more source
Conformation for a beta-cyclodextrin monosubstituted with a cyclic dipeptide. [PDF]
Proceedings of the National Academy of Sciences, 1992 The structural characterization of a beta-cyclodextrin monosubstituted with the peptide cyclo(L-His-L-Leu) is reported. This work provides an x-ray example of a covalently bound group that folds in such a way that the terminal apolar side chain is retained in the hydrophobic interior of the cone-shaped cyclodextrin cavity.
Di Blasio B. +9 more
openaire +7 more sources