Cyclic dipeptides from endophytic bacterium Bacillus velezensis as potential flavor precursors [PDF]
Frontiers in MicrobiologyCyclic dipeptides represent a class of intriguing molecules with a wide range of biological activities, but their potential application as flavor precursors has not been previously reported. In this study, a flavor-producing bacterium Bacillus velezensis
Tianxiao Li +10 more
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Biomimetic epoxidation in aqueous media catalyzed by cyclic dipeptides [PDF]
Synthetic Communications, 2016 We have developed a practical epoxidation of electron-deficient enones in aqueous media using cyclic dipeptides as bioinspired green catalyst. Optimizing the reaction conditions in a triphasic system led to efficient conditions providing epoxides with good enantioselectivities.
Normand Voyer, Christopher Berube
exaly +4 more sources
The Biological Activity of Selected Cyclic Dipeptides [PDF]
Journal of Pharmacy and Pharmacology, 1998 Abstract Cyclic dipeptides are widely used as models for larger peptides because of their simplicity and limited conformational freedom. Some cyclic dipeptides have been shown to be antiviral, antibiotic and anti-tumour. The aim of this study was to determine the biological activity of four cyclic dipeptides synthesized in this ...
P J, Milne +4 more
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A minimalistic hydrolase based on co-assembled cyclic dipeptides [PDF]
Organic & Biomolecular Chemistry, 2019 Cyclic dipeptides based on proteinogenic amino acids form higher aggregates in water with an enzyme-like activity. Are they relevant for abiogenesis?
Alexander Kleinsmann, Boris Nachtsheim
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C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities [PDF]
Molecules, 2020 Prenylated natural products have interesting pharmacological properties and prenylation reactions play crucial roles in controlling the activities of biomolecules.
Rui Liu +5 more
doaj +2 more sources
Induction of mitochondria-mediated apoptosis and suppression of tumor growth in zebrafish xenograft model by cyclic dipeptides identified from Exiguobacterium acetylicum [PDF]
Scientific Reports, 2020 Colorectal cancer is the most common type of gastrointestinal cancers with poor survival and limited therapeutic options. In this study, four structurally different cyclic dipeptides (or diketopiperazine) were isolated and identified as cyclo (l-Pro-l ...
Sekar Jinendiran +7 more
doaj +2 more sources
Cyclic Dipeptides Mediating Quorum Sensing and Their Biological Effects in Hypsizygus Marmoreus [PDF]
Biomolecules, 2020 A novel quorum sensing (QS) system was discovered in Serratia odorifera, the symbiotic bacterium of Hypsizygus marmoreus. This system uses cyclo(Pro-Phe), cyclo(Pro-Tyr), cyclo(Pro-Val), cyclo(Pro-Leu), cyclo(Tyr-Leu), and cyclo(Tyr-Ile) as autoinducers.
Shu-Jing Sun +6 more
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Cyclic Dipeptides in the Induction of Maturation for Cancer Therapy [PDF]
Journal of Pharmacy and Pharmacology, 2000 Abstract Studies have suggested a possible form of therapy based on the use of maturation-inducing compounds to induce differentiation of neoplastic cells and stimulate faster recovery of the normal cell population. The study of the effects of nine cyclic dipeptides on biochemical markers of differentiation implicated their potential to ...
Graz, CJM +5 more
openaire +4 more sources
Identification of Cyclic Dipeptides and a New Compound (6-(5-Hydroxy-6-methylheptyl)-5,6-dihydro-2H-pyran-2-one) Produced by Streptomyces fungicidicus against Alternaria solani [PDF]
Molecules, 2022 As an important microbial resource, Actinomycetes, especially Streptomyces, have important application values in medicine and biotechnology. Streptomyces fungicidicus SYH3 was isolated from soil samples in tomato-growing areas and showed good inhibitory ...
He Liu +11 more
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Increase in blood-transferable linear and cyclic dipeptides in human plasma following ingestion of elastin hydrolysate [PDF]
Food Hydrocolloids for HealthIn this study, we analyzed the absorption of linear and cyclic dipeptides containing Gly, Pro, Ala, and Val by human blood following the ingestion of elastin hydrolysate.
Yu Iwasaki +4 more
doaj +2 more sources