Results 41 to 50 of about 10,177 (227)
Molecules, 2021 Pyrazines (1,4-diazirines) are an important group of natural products that have tremendous monetary value in the food and fragrance industries and can exhibit a wide range of biological effects including antineoplastic, antidiabetic and antibiotic ...
Hong-Bing Liu +6 more
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The Biological Activity of Selected Cyclic Dipeptides
Journal of Pharmacy and Pharmacology, 1998 Abstract Cyclic dipeptides are widely used as models for larger peptides because of their simplicity and limited conformational freedom. Some cyclic dipeptides have been shown to be antiviral, antibiotic and anti-tumour. The aim of this study was to determine the biological activity of four cyclic dipeptides synthesized in this ...
P J, Milne +4 more
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Sequence‐Modulated Active Tripeptide Condensates for Tandem Catalysis
Angewandte Chemie, EarlyView.Sequence‐modulated tripeptide coacervates mimic biomolecular condensates with controllable, enzyme‐regulated phase separation. They co‐sequester hydrophobic active species and hydrophilic enzymes, enabling tandem catalysis in aqueous media. Incorporated into artificial cells, they function as adaptive sub‐organelles, orchestrating compartmentalized ...
Hao Han +7 more
wiley +2 more sources
Frontiers in Microbiology, 2022 The quorum-sensing (QS) cascade is responsible for the colonization and phenotypic behavior of the pathogenic organism and the regulation of diverse signal molecules.
Chintan Kapadia +8 more
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Angewandte Chemie, EarlyView.This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe +5 more
wiley +2 more sources
Food Hydrocolloids for HealthIn this study, we analyzed the absorption of linear and cyclic dipeptides containing Gly, Pro, Ala, and Val by human blood following the ingestion of elastin hydrolysate.
Yu Iwasaki +4 more
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A minimalistic hydrolase based on co-assembled cyclic dipeptides [PDF]
Organic & Biomolecular Chemistry, 2019 Cyclic dipeptides based on proteinogenic amino acids form higher aggregates in water with an enzyme-like activity. Are they relevant for abiogenesis?
Alexander Kleinsmann, Boris Nachtsheim
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Antifungal activity of lactic acid bacteria [PDF]
, 2003 Enrichment culture techniques produced more than 1200 isolates of lactic acid bacteria (LAB) that were screened for antifungal activity against the indicator mould Aspergillus fumigatus. Approximately 10% of the LAB were active, but only 4% had medium or
Magnusson, Jesper
core
One-Pot Synthesis of Nα-Protected Amino/Peptide O-benzyl Hydroxamates and Acylaminoxy Dipeptides Employing Hydroxamic Acid [PDF]
, 2016 The direct conversion of simple and sterically hindered Nα-protected amino/peptide hydroxamic acids to O-benzyl hydroxamates employing K2CO3, tetrabutylammonium bromide and benzyl bromide is described.
Krishnamurthy, Muniyappa. +2 more
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Cyclic dipeptides and the human microbiome: Opportunities and challenges
Bioorganic & Medicinal Chemistry, 2023 Research into the human microbiome has implicated its constituents in a variety of non-communicable diseases, with certain microbes found to promote health and others leading to dysbiosis and pathogenesis.Microbes communicate and coordinate their behaviour through the secretion of small molecules, such as cyclic dipeptides (CDPs), into their ...
Ogilvie, Charlene Elizabeth +1 more
openaire +3 more sources