Results 151 to 160 of about 36,202 (265)

The Regulatory Network of Cyclic GMP-AMP Synthase-Stimulator of Interferon Genes Pathway in Viral Evasion. [PDF]

Front Microbiol, 2021
Hu T, Pan M, Pan M, Yin Y, Wang C, Cui Y, Wang Q.   +6 more
europepmc   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Regulation and Pharmacology of the Cyclic GMP and Nitric Oxide Pathway in Embryonic and Adult Stem Cells. [PDF]

Cells
Kots AY, Bian K.
europepmc   +1 more source

Regulation of cardiac ryanodine receptor function by the cyclic-GMP dependent protein kinase G. [PDF]

Curr Res Physiol, 2022
Gonano LA, Aitken-Buck HM, Chakraborty AD, Worthington LPI, Cully TR, Lamberts RR, Vila-Petroff MG, Jones PP.   +7 more
europepmc   +1 more source

Dynamic Facial Expression Recognition of Learners via Adaptive Global Attention and Differential Temporal Transformer

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Analysing learners' facial expressions during learning and exploring their learning processes and emotional changes are of great significance for assisting teachers' teaching and promoting smart education. In complex learning environments, static facial expression recognition fails to capture the dynamic changes of learners' expressions losing
Wei Liu, Lujia Li, Chun Yan, Yulin Zhang, Xiaochun Cheng, Xinyan Zhao, Mingshi Liu   +6 more
wiley   +1 more source

Inhibitors of the Cyclic GMP-AMP Synthase (cGAS) as Potential Treatment for Autoimmune and Inflammatory Diseases. [PDF]

ACS Med Chem Lett
Abdel-Magid AF.
europepmc   +1 more source

Interference on Cytosolic DNA Activation Attenuates Sepsis Severity: Experiments on Cyclic GMP-AMP Synthase (cGAS) Deficient Mice. [PDF]

Int J Mol Sci, 2021
Visitchanakun P, Kaewduangduen W, Chareonsappakit A, Susantitaphong P, Pisitkun P, Ritprajak P, Townamchai N, Leelahavanichkul A.   +7 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Cyclic GMP-AMP Synthase (cGAS) Deletion Promotes Less Prominent Inflammatory Macrophages and Sepsis Severity in Catheter-Induced Infection and LPS Injection Models. [PDF]

Int J Mol Sci
Suksamai C, Kaewduangduen W, Phuengmaung P, Sae-Khow K, Charoensappakit A, Udomkarnjananun S, Lotinun S, Kueanjinda P, Leelahavanichkul A.   +8 more
europepmc   +1 more source

Natriuretic peptide receptor B maintains heart rate and sinoatrial node function via cyclic GMP-mediated signalling. [PDF]

Cardiovasc Res, 2022
Dorey TW, Mackasey M, Jansen HJ, McRae MD, Bohne LJ, Liu Y, Belke DD, Atkinson L, Rose RA.   +8 more
europepmc   +1 more source