Results 171 to 180 of about 611,110 (302)

An acyclic nucleoside phosphonate effectively blocks the egress of the malaria parasite by inhibiting the synthesis of cyclic GMP. [PDF]

Sci Adv
Ali M, Dura R, Guery MA, Colard-Itté E, Cheviet T, Robresco L, Berry L, Lionne C, Lavazec C, Claessens A, Peyrottes S, Wengelnik K, Wein S, Cerdan R.   +13 more
europepmc   +1 more source

Cyclic GMP-AMP Synthase (cGAS) Deletion Reduces Severity in Bilateral Nephrectomy Mice through Changes in Neutrophil Extracellular Traps and Mitochondrial Respiration. [PDF]

Biomedicines, 2023
Suksawad N, Udompornpitak K, Thawinpipat N, Korwattanamongkol P, Visitchanakun P, Phuengmaung P, Saisorn W, Kueanjinda P, Leelahavanichkul A.   +8 more
europepmc   +1 more source

S100A8/A9 Drives Emergency Granulopoiesis to Promote Triple‐Negative Breast Cancer Metastasis

iNew Medicine, EarlyView.
ABSTRACT Objective Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential and limited therapeutic options. Although neutrophils contribute to tumor progression, how tumors systemically regulate neutrophil production remains poorly understood.
Hami Hemati, Dong Li, Younhee Park, Jinpeng Liu, Xueqing Wang, Xia Liu   +5 more
wiley   +1 more source

Bridging innate immunity and iron-dependent death: the interplay between cyclic GMP-AMP synthase-stimulator of interferon genes nexus and ferroptosis in cancer and inflammation. [PDF]

Front Cell Dev Biol
Chen XX, Hou YQ, Chen XX, Zhou Q, Wang X.   +4 more
europepmc   +1 more source

Cyclic GMP in Liver Cirrhosis-Role in Pathophysiology of Portal Hypertension and Therapeutic Implications. [PDF]

Int J Mol Sci, 2021
Kreisel W, Lazaro A, Trebicka J, Grosse Perdekamp M, Schmitt-Graeff A, Deibert P.   +5 more
europepmc   +1 more source

Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio, Marjori Lima Boblitz Parente, Ronald Feitosa Pinheiro   +2 more
wiley   +1 more source

The radiotherapy induced cyclic GMP-AMP-synthase re-localization and immune signature predicts HNSCC treatment efficacy. [PDF]

Commun Med (Lond)
Mekers VE, Span PN, Looman M, van den Bogaard L, Kho V, Melchers WJG, Bussink J, Kaanders JHAM, Ansems M, Adema GJ.   +9 more
europepmc   +1 more source

Receptor Guanylyl Cyclase C and Cyclic GMP in Health and Disease: Perspectives and Therapeutic Opportunities. [PDF]

Front Endocrinol (Lausanne), 2022
Prasad H, Mathew JKK, Visweswariah SS.
europepmc   +1 more source

Cross‐regional and temporal generalizability of portable visible spectroscopy for olive maturity classification

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Olive maturity governs lot destination and the yield–quality trade‐off in olive oil production, yet it is still monitored by subjective visual scoring of the Jaén index. Spectroscopic alternatives have relied mainly on near‐infrared instruments, with scarce evidence from Brazilian orchards and almost no evaluation of spatial or ...
David Mojaravscki, Paulo S Graziano Magalhães   +1 more
wiley   +1 more source

Association of elevated cyclic GMP levels with hemodynamic changes in HFrEF patients treated with sacubitril/valsartan and vericiguat: a pilot study. [PDF]

Int J Cardiol Heart Vasc
Inoue T, Takahama H, Suzuki H, Arai M, Kikuchi N, Satoh T, Yaoita N, Yamamoto S, Nochioka K, Nakano M, Tatebe S, Takahashi J, Minamino N, Yasuda S.   +13 more
europepmc   +1 more source