Results 241 to 250 of about 611,110 (302)

Specificity of the Cyclic GMP-Bbmding Activity and of a Cyclic GMP-Dependent Cyclic GMP Phosphodiesterase in Dictyostelium discoideum [PDF]

open access: yesMolecular and Cellular Endocrinology, 1982
The nucleotide specificity of the cyclic GMP-binding activity in a homogenate of Dictyostelium discoideum was determined by competition of cyclic GMP derivatives with [8-3H]-cyclic GMP for the binding sites. The results indicate that cyclic GMP is bound to the binding proteins by hydrogen bonds at N2H2, N1-H and/or C6 = O, N7, 2(1)-OH and 3(1)-O and ...
Roman Bulgakov   +2 more
exaly   +6 more sources

Cyclic di-GMP: second messenger extraordinaire [PDF]

open access: yesNature Reviews Microbiology, 2017
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di-GMP).
Urs Jenal
exaly   +2 more sources
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Cyclic AMP and cyclic GMP in hyperresponsiveness

Life Sciences, 1988
Cyclic-AMP has been shown to cause a hyperresponse in blood pressure change in conjunction with norepinephrine in the anesthetized rat system. Recent experiments show that the antagonist to angiotensin II, Sar1-Thr8 angiotensin II, abolishes the hyperresponse produced by c-AMP.
H T, Miller   +3 more
openaire   +2 more sources

Cyclic GMP transporters

Neurochemistry International, 2004
The biokinetics of guanosine 3',5'-cyclic monophosphate (cGMP) is characterized by three distinct processes: synthesis by guanylate cyclases (GCs), conversion of cGMP to GMP by cyclic nucleotide phosphodiesterases (PDEs) and the excretion of unchanged cGMP by transport proteins in the cell membrane.
openaire   +2 more sources

Primary Structure and Functional Expression From Complementary DNA of the Rod Photoreceptor Cyclic GMP-Gated Channel [PDF]

open access: yesNature, 1989
The complete amino-acid sequence of the cyclic GMP-gated channel from bovine retinal rod photo-receptors, deduced by cloning and sequencing its complementary DNA, shows that the protein contains several putative transmembrane segments, followed by a ...
Ulrich Benjamin Kaupp   +2 more
exaly   +2 more sources

Cyclic GMP and photoreceptor function

The FASEB Journal, 1990
A single photon can be detected by a rod photoreceptor cell. The absorption of light by rhodopsin triggers a cascade of reactions that amplifies the photon signal and results in ion channel closure with hyperpolarization of the rod photoreceptor cell.
R N, Lolley, R H, Lee
openaire   +2 more sources

Cyclic GMP signaling in podocytes

Microscopy Research and Technique, 2002
AbstractNatriuretic peptides (NP), together with nitric oxide (NO) are powerful relaxing factors acting via a common second messenger, cyclic GMP (cGMP). Together with other vasoactive modulators, these vasorelaxing factors play an essential role in regulating the function of kidney glomeruli.
Barbara, Lewko, Jan, Stepinski
openaire   +2 more sources

Cyclic GMP in Lower Forms

1994
Publisher Summary This chapter focuses on the lower forms of life—that is, single-celled organisms. It briefly reviews the literature on cyclic guanosine monophosphate (cGMP) in bacteria and then describes two systems that have been studied frequently—the slime mold ( Dictyostelium discoideum ) and the protozoans ( Paramecium and Tetrahymena ). The
J E, Schultz, S, Klumpp
openaire   +2 more sources

Cyclic GMP and Cell Movement

Nature, 1973
THE movement of mammalian cells can be inhibited by agents which mimic or produce increases in the intracellular levels of cyclic 3′,5′-adenosine monophosphate (cyclic AMP)1,2. Goldberg and coworkers3,4 have proposed that in a number of cell types cyclic 3′,5′-guanosine monophosphate (cyclic GMP) promotes cellular events that are antagonistic to those ...
R D, Estensen   +4 more
openaire   +2 more sources

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