Results 91 to 100 of about 90,964 (311)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Construction of regular quasi-cyclic protograph LDPC codes based on Vandermonde matrices
, 2008 In this contribution, we investigate the attainable performance of quasi-cyclic (QC) protograph Low-Density Parity-Check (LDPC) codes for transmission over both Additive White Gaussian Noise (AWGN) and uncorrelated Rayleigh channels.
Sheng Chen +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Experimental study on mechanical response of anchored fractured coal under cyclic dynamic loading
Meikuang AnquanIn order to understand the mechanical response and failure characteristics of anchored fractured coal body under cyclic dynamic load, the dynamic load impact test of anchored fractured coal under cyclic impact dynamic load was carried out by using the ...
Zhen’an LI, Zhuang LI
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
ANALYSIS OF CONSOLIDATION BEHAVIOR OF SUBSOILS UNDER CYCLIC TRAPEZOIDAL LOADING
Journal of Engineering, 2009 This paper is aiming to develop a numerical procedure using the finite element method for the analysis of soil consolidation by taking into consideration the loading and unloading cycles with particular emphases on the pore pressure built up.
Zainab Ahmed Alkaissi +1 more
doaj +1 more source
, 2013 It is important to be able to calculate the ratchet limit of a component when performing integrity assessments of plant components. This paper details the addition of a lower bound ratchet limit calculation to the Linear Matching Method. The extension of
Tipping, David +2 more
core +1 more source
Comparison between defects and micro-notches in multiaxial fatigue – The size effect and the gradient effect [PDF]
, 2009 Lien vers la version éditeur: http://www.sciencedirect.com/science/article/pii/S0142112308002156This paper attempts to improve the understanding of the multiaxial high cycle fatigue response of micro sized stress concentrations or notches of different ...
MOREL, Franck, NADOT, Yves, MOREL, Anne
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Cyclic Load Impact Assessment of Long-Term Properties in Compression to Steel and Polyvinyl Alcohol Fibre-Reinforced Geopolymer Composites. [PDF]
Materials (Basel), 2023 Gailitis R +4 more
europepmc +1 more source