Results 71 to 80 of about 90,964 (311)
, 2011 In this paper a centre cracked plate subjected to cyclic tensile loading and cyclic bending moment is considered. The effect of circular holes drilled in the region of the crack tip on the ratchet limit and crack tip plastic strain range is studied ...
Ure, James Michael +7 more
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Study on the Effect of Cyclic Loading on the Geomechanics of Sandstone Reservoirs in Gas Storage
International Journal of Chemical EngineeringIn the implementation process of carbon capture and storage (CCS), the geomechanical problems arising from the cyclic injection of carbon dioxide into the formation cannot be ignored.
Zhao Xiaolong +8 more
doaj +1 more source
An experimental investigation of cyclically, axially loaded piles in sand
, 1993 Bibliography: leaves 91-93.The research work involved the installation and cyclic load testing of large-scale pressure-grouted, instrumented piles in sand in the laboratory.
Cowburn, S J, S. J. Cowburn
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cyclic J integral using linear matching method
, 2012 The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core
On the cyclic J-integral of a 3D semi elliptical surface crack
, 2014 This paper investigates an approach for calculating the cyclic J-Integral (ΔJ) through a new industrial application. A previously proposed method is investigated further with the extension of this technique through a new application of a practical 3D ...
Hughes, Martin +5 more
core +1 more source
On the ratchet analysis of a cracked welded pipe [PDF]
, 2011 This paper presents the ratchet limit analysis of a pipe with a symmetric crack in a mismatched weld by using the extended Linear Matching Method (LMM). Two loading conditions are considered: i) a cyclic temperature load and a constant internal pressure;
Ure, James Michael +7 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
矿业科学学报Under cyclic load conditions, rock mass engineering such as tunnels and underground storage is prone to large deformation and collapse due to the gradual deterioration of surrounding rock performance.
WANG Gang +5 more
doaj +1 more source