Results 91 to 100 of about 372,306 (310)

Mixed-mode cyclic debonding of adhesively bonded composite joints [PDF]

A combined experimental-analytical investigation to characterize the cyclic failure mechanism of a simple composite-to-composite bonded joint is conducted.
Mall, S., Rezaizadeh, M. A.
core   +1 more source

Linear matching method on the evaluation of cyclic behaviour with creep effect [PDF]

, 2012
This paper describes a new Linear Matching Method (LMM) technique for the direct evaluation of cyclic behaviour with creep effects of structures subjected to a general load condition in the steady cyclic state.
Chen, Haofeng, Chen, Weihang, Ure, James Michael   +2 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

The Influence of Cyclic Loading on the Mechanical Properties of Well Cement

Energies
The cyclic loading generated by injection and production operations in underground gas storage facilities can lead to fatigue damage to cement sheaths and compromise the integrity of wellbores.
Zhen Zhang, Zhongtao Yuan, Sutao Ye, Yang Li, Lvchao Yang, Xueyu Pang, Kaihe Lv, Jinsheng Sun   +7 more
doaj   +1 more source

Asymptotic homogenisation in strength and fatigue durability analysis of composites [PDF]

This is the post-print version of the Article. Copyright @ 2003 Kluwer Academic Publishers.Asymptotic homogenisation technique and two-scale convergence is used for analysis of macro-strength and fatigue durability of composites with a periodic structure
A. N. Kolmogorov, D. Cioranescu, G. Allaire, N. Bakhvalov, S. E. Mikhailov, V. A. Trenogin   +5 more
core   +1 more source

Cyclic error-locating codes

Information and Control, 1967
A new class of error-locating codes, which are equivalent to cyclic codes, is presented, together with a general decoding procedure. Connections with some previously considered error-locating codes are pointed out.
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Research on the Seismic Performance of Immersion Joints Under Cyclic Loading

Shock and Vibration
Underground traffic structures can ease the traffic pressure on ground traffic and alleviate the effect of urban heat wave. The structural failure of underground structures caused by earthquakes is one of the crucial hazards in the field of urban ...
Xinjun Cheng, Kunpeng Xu, Shiyuan Li, Liping Jing   +3 more
doaj   +1 more source

Advances in Research for Mechanical Characteristics of Vertically Loaded Anchors for Offshore Platforms under Cyclic Loads

Journal of Marine Science and Engineering
Vertically loaded anchors (VLAs) are widely used as mooring foundations in marine environments. Their working conditions typically involve deep-sea seabed, frequently subjected to cyclic loads induced by wind, waves, and currents.
Dapeng Li, Baoliang Zhang, Guoqi Xing, Jian Li   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source