Results 31 to 40 of about 58,754 (258)

Cyclic liquefaction behavior of silty sand considering initial static shear effect: a DEM investigation

open access: yesYantu gongcheng xuebao
To gain more insights into the microscopic mechanism of the liquefaction behavior, the particle flow program PFC3D is used to simulate the liquefaction process of silty sands under undrained cyclic loading.
PAN Kun 1 , LI Peipei 1, CAO Yi 2, WU Qixin 3, YANG Zhongxuan 4
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Monotonic, unidirectional, and bidirectional cyclic simple shear responses of municipal solid waste incineration bottom ash

open access: yesJournal of Rock Mechanics and Geotechnical Engineering
Incineration bottom ash (IBA) holds attractive potential as a construction material, yet its shear behavior under cyclic loading remains insufficiently understood. This study comprehensively characterizes the monotonic and cyclic simple shear behavior of
Zhibo Zhang   +7 more
doaj   +1 more source

Structural Basis of Dual Specificity of Sinorhizobium meliloti Clr, a cAMP and cGMP Receptor Protein

open access: yesmBio, 2023
In bacteria, the most prevalent receptor proteins of 3′,5′-cyclic AMP (cAMP) and 3′,5′-cyclic GMP (cGMP) are found among transcription factors of the Crp-Fnr superfamily.
Laura Werel   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Effect of particle shape on liquefaction and Re-liquefaction strength of short fiber-reinforced sand

open access: yesResults in Engineering
Fiber-reinforcement is a widely studied soil stabilization technique, yet certain aspects of its reinforcing mechanisms and fiber-soil interactions remain unexplored.
Takayuki Sakai   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Principal stress rotation as cause of cyclic mobility [PDF]

open access: yesGeotechnical Research, 2015
Principal stress rotation (PSR) has been known to act as ‘loading’ on soils since the seminal work of Arthur et al. some 30 years ago, using the directional shear cell. However, the key insight – reflected in the titles of the original papers – that soils yield under constant stress invariants if the principal stresses rotate, has been consistently ...
Michael Jefferies   +2 more
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Liquefaction Potential of Silty Sand in Simple Shear [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2013
In this paper, the liquefaction potential of medium dense and dense sand layers was studied by performing constant volume (undrained) cyclic simple shear tests using cyclic simple shear apparatus. Strain-controlled approach was adopted.
Zaheer Ahmed Almani   +2 more
doaj  

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