Results 41 to 50 of about 58,754 (258)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Influences of fines content on cyclic resistance ratio of fines-sand-gravel mixtures

open access: yesYantu gongcheng xuebao, 2017
In the available researches on the cyclic resistance ratio (CRR) of saturated sand-gravel mixtures, the factors such as gravel content, sample preparation method, relative density and consolidation stress ratio have been considered.
WU Qi 1, CHEN Guo-xing 1,2, ZHOU Zheng-long 1, HUANG Bo 3
doaj   +1 more source

Ketamine Reduces the Surface Density of the Astroglial Kir4.1 Channel and Inhibits Voltage-Activated Currents in a Manner Similar to the Action of Ba2+ on K+ Currents

open access: yesCells, 2023
A single sub-anesthetic dose of ketamine evokes rapid and long-lasting beneficial effects in patients with a major depressive disorder. However, the mechanisms underlying this effect are unknown.
Mićo Božić   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Unified Approach To The Modelling of Liquefaction And Cyclic Mobility Of Sands

open access: yesSoils and Foundations, 1981
In this paper the problem of liquefaction of sand under either monotonic or cyclic loading is tackled from the point of view of continuum mechanics. It is shown that a suitable constitutive model may explain, in a phenomenological sense, the generation of pore pressure in an undrained test either when the load is monotonically increased to failure or ...
NOVA, ROBERTO, HUECKEL, TOMASZ
openaire   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The Influence of Mobility Rate on Spiral Waves in Spatial Rock-Paper-Scissors Games

open access: yesGames, 2016
We consider a two-dimensional model of three species in rock-paper-scissors competition and study the self-organisation of the population into fascinating spiraling patterns.
Mauro Mobilia   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Mobility restrictions in response to local epidemic outbreaks in rock-paper-scissors models

open access: yesJournal of Physics: Complexity
We study a three-species cyclic model whose organisms are vulnerable to contamination with an infectious disease which propagates person-to-person. We consider that individuals of one species perform a self-preservation strategy by reducing the mobility ...
J Menezes
doaj   +1 more source

Nonbinary LDPC-Coded Modulation System in High-Speed Mobile Communications

open access: yesIEEE Access, 2018
As a class of capacity-approaching codes, nonbinary low-density parity-check (LDPC) codes have attracted much attention because of noticeable performance.
Dan Feng   +5 more
doaj   +1 more source

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