Results 61 to 70 of about 61,392 (298)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Mechanisms of shear strain accumulation in laboratory experiments on sands exhibiting cyclic mobility behavior [PDF]
, 2022 The factors and mechanisms controlling the accumulation of shear strains of clean uniform sands exhibiting cyclic mobility behavior under level-ground conditions are examined.
Humire, Francisco, Ziotopoulou, Katerina
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The Influence of Mobility Rate on Spiral Waves in Spatial Rock-Paper-Scissors Games
Games, 2016 We consider a two-dimensional model of three species in rock-paper-scissors competition and study the self-organisation of the population into fascinating spiraling patterns.
Mauro Mobilia +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Mobility restrictions in response to local epidemic outbreaks in rock-paper-scissors models
Journal of Physics: ComplexityWe study a three-species cyclic model whose organisms are vulnerable to contamination with an infectious disease which propagates person-to-person. We consider that individuals of one species perform a self-preservation strategy by reducing the mobility ...
J Menezes
doaj +1 more source
Nonbinary LDPC-Coded Modulation System in High-Speed Mobile Communications
IEEE Access, 2018 As a class of capacity-approaching codes, nonbinary low-density parity-check (LDPC) codes have attracted much attention because of noticeable performance.
Dan Feng +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Effect Of Initial Stress Anisotropy on The Cyclic Behaviour of Sand [PDF]
Engineering and Technology Journal, 2005 Due mainly to the process of deposition under earth gravity , the behavior of in situ sand is inherently anisotropic , meaning the stress - strain - strength relations for the same sand may vary as the stress tensor rotates relative to the orientation of
Mohammed Fattah
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source