Results 51 to 60 of about 61,392 (298)

Principal stress rotation as cause of cyclic mobility [PDF]

open access: yesGeotechnical Research, 2015
Principal stress rotation (PSR) has been known to act as ‘loading’ on soils since the seminal work of Arthur et al. some 30 years ago, using the directional shear cell. However, the key insight – reflected in the titles of the original papers – that soils yield under constant stress invariants if the principal stresses rotate, has been consistently ...
Michael Jefferies   +2 more
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Numerical modeling of cyclic mobility based on fuzzy-set concepts in plasticity theory [PDF]

open access: yes, 2020
a b s t r a c t In this paper, the application of an efficient, transparent and accurate kinematic-cyclic constitutive model based on the fuzzy-set concepts and incremental plasticity theory is presented to show its capability in modeling cyclic mobility
Yu Bao, Stein Sture
core  

Seismic reliability-based analysis and GIS mapping of cyclic mobility of clayey soils of Mumbai city, India

open access: yes, 2017
Cyclic mobility is a mechanism of ground failure due to lateral spreading of soils during an earthquake that usually occurs in soft or medium stiff saturated soils.
PHULE, RR, CHOUDHURY, D
core   +2 more sources

Ketamine Reduces the Surface Density of the Astroglial Kir4.1 Channel and Inhibits Voltage-Activated Currents in a Manner Similar to the Action of Ba2+ on K+ Currents

open access: yesCells, 2023
A single sub-anesthetic dose of ketamine evokes rapid and long-lasting beneficial effects in patients with a major depressive disorder. However, the mechanisms underlying this effect are unknown.
Mićo Božić   +6 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Liquefaction Potential of Silty Sand in Simple Shear [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2013
In this paper, the liquefaction potential of medium dense and dense sand layers was studied by performing constant volume (undrained) cyclic simple shear tests using cyclic simple shear apparatus. Strain-controlled approach was adopted.
Zaheer Ahmed Almani   +2 more
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Influences of fines content on cyclic resistance ratio of fines-sand-gravel mixtures

open access: yesYantu gongcheng xuebao, 2017
In the available researches on the cyclic resistance ratio (CRR) of saturated sand-gravel mixtures, the factors such as gravel content, sample preparation method, relative density and consolidation stress ratio have been considered.
WU Qi 1, CHEN Guo-xing 1,2, ZHOU Zheng-long 1, HUANG Bo 3
doaj   +1 more source

A Unified Approach To The Modelling of Liquefaction And Cyclic Mobility Of Sands

open access: yesSoils and Foundations, 1981
In this paper the problem of liquefaction of sand under either monotonic or cyclic loading is tackled from the point of view of continuum mechanics. It is shown that a suitable constitutive model may explain, in a phenomenological sense, the generation of pore pressure in an undrained test either when the load is monotonically increased to failure or ...
NOVA, ROBERTO, HUECKEL, TOMASZ
openaire   +1 more source

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