Results 51 to 60 of about 179,542 (293)
Dynamical Heterogeneity close to the Jamming Transition in a Sheared Granular Material
, 2005 The dynamics of a bi-dimensional dense granular packing under cyclic shear is experimentally investigated close to the jamming transition. Measurement of multi-point correlation functions are produced.
Biroli, G., Dauchot, O., Marty, G.
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Journal of Rock Mechanics and Geotechnical EngineeringIncineration bottom ash (IBA) holds attractive potential as a construction material, yet its shear behavior under cyclic loading remains insufficiently understood. This study comprehensively characterizes the monotonic and cyclic simple shear behavior of
Zhibo Zhang +7 more
doaj +1 more source
Efficiency at maximum power: An analytically solvable model for stochastic heat engines
, 2007 We study a class of cyclic Brownian heat engines in the framework of finite-time thermodynamics. For infinitely long cycle times, the engine works at the Carnot efficiency limit producing, however, zero power. For the efficiency at maximum power, we find
Feynman R. P. +6 more
core +1 more source
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles [PDF]
, 1994 Elevation of cAMP can cause gene-specific inhibition of interleukin 2 (IL-2) expression. To investigate the mechanism of this effect, we have combined electrophoretic mobility shift assays and in vivo genomic footprinting to assess both the availability ...
Chen, Dan, Rothenberg, Ellen V.
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Effect of particle shape on liquefaction and Re-liquefaction strength of short fiber-reinforced sand
Results in EngineeringFiber-reinforcement is a widely studied soil stabilization technique, yet certain aspects of its reinforcing mechanisms and fiber-soil interactions remain unexplored.
Takayuki Sakai +2 more
doaj +1 more source
Cells, 2023 A single sub-anesthetic dose of ketamine evokes rapid and long-lasting beneficial effects in patients with a major depressive disorder. However, the mechanisms underlying this effect are unknown.
Mićo Božić +6 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Wave excitations of drifting two-dimensional electron gas under strong inelastic scattering
, 2012 We have analyzed low-temperature behavior of two-dimensional electron gas in polar heterostructures subjected to a high electric field. When the optical phonon emission is the fastest relaxation process, we have found existence of collective wave-like ...
Kochelap, V. A. +2 more
core +1 more source